Results 11 to 20 of about 38,948 (266)

Modern technologies for radium removal from water – Polish mining industry case study

Water Resources and Industry, 2020
In the formation waters, occurring in coal mines in the Upper Silesian Coal Basin, Poland different pollutants are present which may cause damages to the environment, among them radium isotopes.
Stanisław Chałupnik, Małgorzata Wysocka, Izabela Chmielewska, Krzysztof Samolej   +3 more
doaj   +1 more source

Detection of Mutations in Exon 8 of TP53 by Temperature Gradient 96-Capillary Array Electrophoresis

BioTechniques, 2002
Various capillary electrophoresis applications have increasingly been utilized in mutation detection. Separation of two species is either based on secondary structure or differences in melting of DNA due to the mutation.
A. Torgunrud Kristensen, J. Bjørheim, M. Minarik, K.-E. Giercksky, P.O. Ekstrøm   +4 more
doaj   +1 more source

Radium-223 for metastatic, castration-resistant prostate cancer: A retrospective chart review study of real-world use in a tertiary hospital in Taiwan

Journal of the Formosan Medical Association, 2022
Background: Radium-223 is an alpha-emitting, bone-targeting radiopharmaceutical that confers a survival benefit in patients with confirmed bone-metastatic, castration-resistant prostate cancer with no visceral metastases.
Wei-Chun Weng, Li-Hua Huang, Neng-Chuan Tseng, Yen-Chuan Ou   +3 more
doaj   +1 more source

Automated Constant Denaturant Capillary Electrophoresis Applied for Detection of KRAS Exon 1 Mutations

BioTechniques, 2001
In this study, we have applied automated constant denaturant capillary electrophoresis (ACDCE) for the detection of KRAS exon 1 mutations. Samples from 191 sporadic colon carcinomas previously analyzed for KRAS mutations with allele-specific PCR (ASPCR),
J. Bjørheim, P.O. Ekstrøm, E. Fossberg, A.-L. Børresen-Dale, G. Gaudernack   +4 more
doaj   +1 more source

Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas

BioTechniques, 2005
Mutations in the tumor suppressor gene TP53 are associated with a wide range of different cancers and may have prognostic and therapeutic implications. Methods for rapid and sensitive detection of mutations in this gene are therefore required.
Pedro Kringen, Anna Bergamaschi, Eldri Undlien Due, Yun Wang, Elda Tagliabue, Jahn M. Nesland, Aune Nehman, Neeme Tönisson, Anne-Lise Børresen-Dale   +8 more
doaj   +1 more source

Estimation of radon exhalation rate from a brick wall during various stages of construction by measuring exhalation rates from various building materials

Radiation Protection and Environment, 2020
Radon concentration in a room can be predicted from accurate knowledge of exhalation rates from six surfaces of the room. Walls of a room occupy the maximum surface area of the room.
Manish Kumar, B K Sahoo, Rajesh Kumar, Navjeet Sharma   +3 more
doaj   +1 more source

Clinical outcomes and treatment patterns in REASSURE: planned interim analysis of a real-world observational study of radium-223 in metastatic castration-resistant prostate cancerResearch in context

EClinicalMedicine, 2023
Summary: Background: Radium-223, a targeted alpha therapy, is approved to treat bone-dominant metastatic castration-resistant prostate cancer (mCRPC), based on significantly prolonged overall survival versus placebo and a favourable safety profile in ...
Celestia S. Higano, Daniel J. George, Neal D. Shore, Oliver Sartor, Kurt Miller, Peter S. Conti, Cora N. Sternberg, Fred Saad, Juan Pablo Sade, Joaquim Bellmunt, Matthew R. Smith, Kumari Chandrawansa, Per Sandström, Frank Verholen, Bertrand Tombal   +14 more
doaj   +1 more source

T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

OncoImmunology, 2017
T-cell receptor (TCR) transfer is an attractive strategy to increase the number of cancer-specific T cells in adoptive cell therapy. However, recent clinical and pre-clinical findings indicate that careful consideration of the target antigen is required ...
Else M. Inderberg, Sébastien Wälchli, Marit R. Myhre, Sissel Trachsel, Hilde Almåsbak, Gunnar Kvalheim, Gustav Gaudernack   +6 more
doaj   +1 more source

Radium‐223 dichloride treatment in metastatic castration‐resistant prostate cancer in Finland: A real‐world evidence multicenter study

Cancer Medicine, 2023
Background Radium‐233 dichloride is an alpha emitter that specifically targets bone metastases in prostate cancer. Results of a previously reported phase III randomized trial showed survival benefit for radium‐223 compared to best supportive care in ...
Anniina Hyväkkä, Okko‐Sakari Kääriäinen, Tapio Utriainen, Eliisa Löyttyniemi, Kalle Mattila, Petri Reinikainen, Jorma Sormunen, Minna Jääskeläinen, Päivi Auvinen, Heikki Minn, Maria Sundvall   +10 more
doaj   +1 more source

Dose in biota due to alpha radionuclide emitters in a dan associated with a uranium mining

Brazilian Journal of Radiation Sciences, 2020
Introdução: A  radioproteção tem como foco a proteção dos seres humanos e seus descendentes e a proteção do meio ambiente. A proteção ambiental sempre foi feita de forma indireta por meio da proteção do ser humano no meio ambiente.
Wagner De Souza Pereira, Alphonse Kelecom, Alessander Sá do Carmo, Emanuele Lazzaretti Cordova Campelo, Maxime Charles-Pierre, Lucas Gomes Padilha Filho, Gilvan Cardoso Souza, Jose Marques Lopez   +7 more
doaj   +1 more source