Results 21 to 30 of about 39,669 (259)

Geology of the Pitchblende Deposits of Port Radium, Great Bear Lake, N.W.T. [PDF]

, 1955
The geology of the McTavish Arm area of Great Bear Lake, Northwest Territories, Canada, is reviewed and a geologic map is presented. The geology of the Labine Point region is described in detail.
Campbell, Douglas Dean
core   +1 more source

Radium‐223 dichloride treatment in metastatic castration‐resistant prostate cancer in Finland: A real‐world evidence multicenter study

Cancer Medicine, 2023
Background Radium‐233 dichloride is an alpha emitter that specifically targets bone metastases in prostate cancer. Results of a previously reported phase III randomized trial showed survival benefit for radium‐223 compared to best supportive care in ...
Anniina Hyväkkä, Okko‐Sakari Kääriäinen, Tapio Utriainen, Eliisa Löyttyniemi, Kalle Mattila, Petri Reinikainen, Jorma Sormunen, Minna Jääskeläinen, Päivi Auvinen, Heikki Minn, Maria Sundvall   +10 more
doaj   +1 more source

Radium-223 as an Additional Therapeutic Strategy in Highly Selected Patients With Metastatic Breast Cancer: A Case Report

Frontiers in Oncology, 2022
Radium-223 is commonly used in metastatic prostate cancer, targeting specifically bone metastases. The use of radium-223 remains, however, poorly evaluated in metastatic breast cancer.
Hélène Houssiau, Francois P. Duhoux, Didier François, Emmanuel Seront   +3 more
doaj   +1 more source

The problem of skipped generation and subclinical disease in familial breast‐ovarian cancer

Acta Obstetricia et Gynecologica Scandinavica, 1997
Background. The major gene for inherited breast ovarian cancer families shows high penetrance in female carriers. Daughters of living unaffected women in these families are supposed to have a low risk of cancer.
Anne Dørum, Vera M. Abeler, Ketil Heimdal, Claes Tropé, Pål Møller   +4 more
doaj   +1 more source

Extended X-ray absorption fine structure spectroscopy measurements and ab initio molecular dynamics simulations reveal the hydration structure of the radium(II) ion

iScience, 2022
Summary: Radium is refocused from the viewpoint of an environmental pollutant and cancer therapy using alpha particles, where it mainly exists as a hydrated ion.
Akiko Yamaguchi, Kojiro Nagata, Keita Kobayashi, Kazuya Tanaka, Tohru Kobayashi, Hajime Tanida, Kojiro Shimojo, Tetsuhiro Sekiguchi, Yui Kaneta, Shohei Matsuda, Keiichi Yokoyama, Tsuyoshi Yaita, Takashi Yoshimura, Masahiko Okumura, Yoshio Takahashi   +14 more
doaj   +1 more source

Naturally occurring radium (Ra) in home drinking‐water wells in the Sandhills region of South Carolina, USA: Can high concentrations be predicted?

GeoHealth, 2017
A strong relationship exists between concentrations of several principal constituents of water chemistry and naturally occurring radium in water from home wells in the large Sandhills region of the inner coastal plain of South Carolina, United States, an
Jeffrey M. Schrag
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

An analysis of hazard indices based on the transfer factor of naturally occurring radionuclides in herbal infusions [PDF]

Anais da Academia Brasileira de Ciências
The transfer factor is an important concept for assessing hazard indices associated with radionuclide intake. In this study, radionuclide transfer factors were determined for the infusion process using gamma spectrometry.
ROBERTO C. SILVA, JOSÉ M. LOPES, LUCAS F. SILVA, ALESSANDRO M. DOMINGUES, WAGNER S. PEREIRA, ADEMIR X. SILVA   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source