Results 11 to 20 of about 39,669 (259)

Automated Constant Denaturant Capillary Electrophoresis Applied for Detection of KRAS Exon 1 Mutations

BioTechniques, 2001
In this study, we have applied automated constant denaturant capillary electrophoresis (ACDCE) for the detection of KRAS exon 1 mutations. Samples from 191 sporadic colon carcinomas previously analyzed for KRAS mutations with allele-specific PCR (ASPCR),
J. Bjørheim, P.O. Ekstrøm, E. Fossberg, A.-L. Børresen-Dale, G. Gaudernack   +4 more
doaj   +1 more source

Dose in biota due to alpha radionuclide emitters in a dan associated with a uranium mining

Brazilian Journal of Radiation Sciences, 2020
Introdução: A  radioproteção tem como foco a proteção dos seres humanos e seus descendentes e a proteção do meio ambiente. A proteção ambiental sempre foi feita de forma indireta por meio da proteção do ser humano no meio ambiente.
Wagner De Souza Pereira, Alphonse Kelecom, Alessander Sá do Carmo, Emanuele Lazzaretti Cordova Campelo, Maxime Charles-Pierre, Lucas Gomes Padilha Filho, Gilvan Cardoso Souza, Jose Marques Lopez   +7 more
doaj   +1 more source

Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas

BioTechniques, 2005
Mutations in the tumor suppressor gene TP53 are associated with a wide range of different cancers and may have prognostic and therapeutic implications. Methods for rapid and sensitive detection of mutations in this gene are therefore required.
Pedro Kringen, Anna Bergamaschi, Eldri Undlien Due, Yun Wang, Elda Tagliabue, Jahn M. Nesland, Aune Nehman, Neeme Tönisson, Anne-Lise Børresen-Dale   +8 more
doaj   +1 more source

Clinical outcomes and treatment patterns in REASSURE: planned interim analysis of a real-world observational study of radium-223 in metastatic castration-resistant prostate cancerResearch in context

EClinicalMedicine, 2023
Summary: Background: Radium-223, a targeted alpha therapy, is approved to treat bone-dominant metastatic castration-resistant prostate cancer (mCRPC), based on significantly prolonged overall survival versus placebo and a favourable safety profile in ...
Celestia S. Higano, Daniel J. George, Neal D. Shore, Oliver Sartor, Kurt Miller, Peter S. Conti, Cora N. Sternberg, Fred Saad, Juan Pablo Sade, Joaquim Bellmunt, Matthew R. Smith, Kumari Chandrawansa, Per Sandström, Frank Verholen, Bertrand Tombal   +14 more
doaj   +1 more source

The reverse protraction factor in the induction of bone sarcomas in radium-224 patients [PDF]

, 1990
More than 50 bone sarcomas have occurred among a collective of about 800 patients who had been injected in Germany after World War II with large activities of radium-224 for the intended treatment of bone tuberculosis and ankylosing spondylitis.^In an ...
Kellerer, Albrecht M., Chmelevsky, D., Spiess, H., Mays, C. W.   +3 more
core   +2 more sources

T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth

OncoImmunology, 2017
T-cell receptor (TCR) transfer is an attractive strategy to increase the number of cancer-specific T cells in adoptive cell therapy. However, recent clinical and pre-clinical findings indicate that careful consideration of the target antigen is required ...
Else M. Inderberg, Sébastien Wälchli, Marit R. Myhre, Sissel Trachsel, Hilde Almåsbak, Gunnar Kvalheim, Gustav Gaudernack   +6 more
doaj   +1 more source

Estimation of radon exhalation rate from a brick wall during various stages of construction by measuring exhalation rates from various building materials

Radiation Protection and Environment, 2020
Radon concentration in a room can be predicted from accurate knowledge of exhalation rates from six surfaces of the room. Walls of a room occupy the maximum surface area of the room.
Manish Kumar, B K Sahoo, Rajesh Kumar, Navjeet Sharma   +3 more
doaj   +1 more source

Radium-223 for metastatic, castration-resistant prostate cancer: A retrospective chart review study of real-world use in a tertiary hospital in Taiwan

Journal of the Formosan Medical Association, 2022
Background: Radium-223 is an alpha-emitting, bone-targeting radiopharmaceutical that confers a survival benefit in patients with confirmed bone-metastatic, castration-resistant prostate cancer with no visceral metastases.
Wei-Chun Weng, Li-Hua Huang, Neng-Chuan Tseng, Yen-Chuan Ou   +3 more
doaj   +1 more source

Time and dose dependency of bone-sarcomas in patients injected with radium-224 [PDF]

, 1988
The time course and dose dependency of the incidence of bone-sarcomas among 900 German patients treated with high doses of radium-224 is analysed in terms of a proportional hazards model with a log-normal dependency of time to tumor and a linear ...
Land, C.E., Kellerer, Albrecht M., Mays, C.W., Chmelevsky, D., Spiess, H., Land, C. E., Kellerer, A.M., Mays, C. W., Spieß, H.F., H. Spiess, D. Chmelevsky, C. W. Mays, C. E. Land, A. M. Kellerer   +13 more
core   +1 more source

Sorption pre/concentration of alkaline earth elements from natural waters within the method of radiochemical analysis

Водное хозяйство России: проблемы, технологии, управление, 2022
Development of novel methods of the radiochemical analysis for natural and artificial radionuclides is one of the most urgent current tasks. Th is work deals with studying of laws of sorption pre/concentration of strontium and radium radionuclides in ...
Vladimir S. Semenishchev, Anna V. Voronina, Svetlana M. Titova, Yulia I. Nasonova, Maria A. Cherepanova   +4 more
doaj   +1 more source