Results 11 to 20 of about 464,345 (215)

A phase 1b study evaluating the effect of elacestrant treatment on estrogen receptor availability and estradiol binding to the estrogen receptor in metastatic breast cancer lesions using 18F-FES PET/CT imaging

Breast Cancer Research, 2020
Background Elacestrant is an oral selective estrogen receptor (ER) degrader. This phase 1b open-label, non-randomized study (RAD1901-106) was initiated to determine the effect of elacestrant on the availability of ER in lesions from postmenopausal women ...
Agnes Jager, Elisabeth G. E. de Vries, C. Willemien Menke-van der Houven van Oordt, Patrick Neven, Clasina M. Venema, Andor W. J. M. Glaudemans, Yamei Wang, Rebecca G. Bagley, Maureen G. Conlan, Philippe Aftimos   +9 more
doaj   +1 more source

Insects as Diet and Therapy: Perspectives on Their Use for Combating Diabetes Mellitus in Tanzania

Pharmaceuticals, 2021
More than 450 million people worldwide are suffering from diabetes and this number is expected to increase. In developing countries, such as Tanzania, the number of patients suffering from diabetes and associated diseases is increasing as well. Up to 80%
Geert René Verheyen, Luc Pieters, Sheila Maregesi, Sabine Van Miert   +3 more
doaj   +1 more source

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors

Breast Cancer Research, 2019
Background Addition of CDK4/6 inhibitors (CDK4/6i) to endocrine therapy significantly increased progression-free survival, leading to their approval and incorporation into the metastatic breast cancer treatment paradigm.
Hitisha K. Patel, Nianjun Tao, Kyung-Min Lee, Mariela Huerta, Heike Arlt, Tara Mullarkey, Steven Troy, Carlos L. Arteaga, Teeru Bihani   +8 more
doaj   +1 more source

Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study

JBMR Plus, 2020
Type 2 diabetes mellitus (T2DM) increases fracture risk despite normal or increased BMD. Abaloparatide reduces fracture risk in patients with postmenopausal osteoporosis (PMO); however, its efficacy in women with T2DM is unknown.
Ruban Dhaliwal, Didier Hans, Gary Hattersley, Bruce Mitlak, Lorraine A Fitzpatrick, Yamei Wang, Ann V Schwartz, Paul D Miller, Robert G Josse   +8 more
doaj   +1 more source

Bilateral Monteggia fracture in adults [PDF]

Vojnosanitetski Pregled, 2011
Introduction. In 1814 Giovanni Monteggia first described two cases of fractures of the proximal third of ulna with dislocation of the radial head. These fractures are more common in children than in adults, and mutual Monteggia fracture is a rare ...
Ristić Dejan, Jovanović Nebojša, Cvetković Voja, Stanković Biljana, Vračević Branislav   +4 more
doaj   +1 more source

Reliability Comparison between “Distal Radius and Ulna” and “Simplified Tanner–Whitehouse III” Assessments for Patients with Adolescent Idiopathic Scoliosis [PDF]

Asian Spine Journal, 2020
Study Design This is a retrospective clinical study. Purpose In this study, we aim to evaluate the reliability of the distal radius and ulna assessment (DRU) and simplified Tanner-Whitehouse III classification (sTW3) in Japanese patients with adolescent ...
Akinori Okuda, Hideki Shigematsu, Hiromasa Fujii, Eiichiro Iwata, Masato Tanaka, Yasuhiko Morimoto, Keisuke Masuda, Yusuke Yamamoto, Yasuhito Tanaka   +8 more
doaj   +1 more source

Evaluation of the Radial Procurvatum Using the Center of Rotation of Angulation Methodology in Chondrodystrophic Dogs

Frontiers in Veterinary Science, 2022
The radial joint orientation angles were calculated using the center of rotation of angulation (CORA) methodology within the frontal and sagittal planes in chondrodystrophic dog breeds, including Welsh Corgi, Dachshund, Pekinese, Poodle, Beagle and ...
Minji Kwon, Danbee Kwon, Jonghyop Lee, Kichang Lee, Hakyoung Yoon   +4 more
doaj   +1 more source

Usaha Meubel Jedong Sekarputih Balongpanggang Gresik

Aksiologiya: Jurnal Pengabdian Kepada Masyarakat, 2017
In this program partner SMEs are SMEs whose products are handicrafts Furniture in Jedong Sekarputih Balongpanggang Gresik.UKM involved partner there are 2, namely: UD. Future Furnituredan UD.Kharisma Meubel.
Radius Setiawan
doaj   +1 more source

Response rates for hip, femoral neck, and lumbar spine bone mineral density in patients treated with abaloparatide followed by alendronate: Results from phase 3 ACTIVExtend

Bone Reports, 2019
Abaloparatide is a selective activator of the parathyroid hormone type 1 receptor signaling pathway that favors the stimulation of bone formation. Here, we report a prospective, exploratory analysis of bone mineral density (BMD) response rates comparing ...
Chad L. Deal, Bruce H. Mitlak, Yamei Wang, Lorraine A. Fitzpatrick, Paul D. Miller   +4 more
doaj   +1 more source

Radius-invariant graphs [PDF]

Mathematica Bohemica, 2004
Summary: The eccentricity \(e(v)\) of a vertex \(v\) is defined as the distance to a farthest vertex from \(v\). The radius of a graph \(G\) is defined as \(r(G)=\min _{u \in V(G)}\{ e(u)\}\). A graph \(G\) is radius-edge-invariant if \(r(G-e)=r(G)\) for every \(e \in E(G)\), radius-vertex-invariant if \(r(G-v)= r(G)\) for every \(v \in V(G)\) and ...
Bálint, V., Vaček, O.
openaire   +2 more sources