Results 71 to 80 of about 724,109 (262)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A generalization of the numerical radius

Linear Algebra and its Applications, 2019
We define a norm on the space of bounded linear operators on a Hilbert space, which generalizes the numerical radius norm. We investigate basic properties of this norm and prove inequalities involving it. A concrete example of this norm is also given.
A. Abu-Omar, F. Kıttaneh
semanticscholar   +1 more source

Radius Prawiro: kiprah, peran dan pemikiran [PDF]

, 2002
Begitulah sebuah dialektika tengah dan masih akan terus berlangsung. Pikiran-pikiran besar yang cenderung idealistis pada masa kejayaan Sukarno diganti dengan pikiran-pikiran pragmatis pada Soeharto.
Radius Prawiro
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Is dorsal cortex drilling necessary for distal radius fractures treated with a volar locking plate? A comparative study of near-cortex-only and far-cortex drilling [PDF]

Journal of Trauma and Injury
Purpose This study aimed to compare and analyze the effectiveness of near-cortex-only drilling for the surgical treatment of distal radius fractures using a volar locking plate.
Chul Hong Kim, Sung Yoon Jung, Hyeon Jun Kim, Si-Hyun Park   +3 more
doaj   +1 more source

Practical Method to Evaluate the Stiffness of Fractured Radius

Methods and Protocols, 2023
Distal radius fractures (DRFs) are one of the most common fractures of the upper extremity system. To evaluate the performance of DRF treatments, the construct (i.e., a DRF fixed by an implant) was compressed at the distal radius in the axial direction ...
Nitikorn Noraphaiphipaksa, Surangkana Katepun, Thanapong Waitayawinyu, Chaosuan Kanchanomai   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Inequalities for some Functionals Associated with Bounded Linear Operators in Hilbert Spaces

, 2006
Some inequalities between the operator norm, numerical radius and functional are established. New upper bounds for the nonnegative quantity that complement some recent results of the author are given as ...
Dragomir, Sever S
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Geometry repeatability and prediction for personalized medical devices made using multi-jet fusion additive manufacturing

Additive Manufacturing Letters
As additive manufacturing (AM) production volumes grow to the industrial scale, quality systems must also scale to verify that every part satisfies requirements.
Christopher H. Conway, Davis J. McGregor, Tristan Antonsen, Charles Wood, Chenhui Shao, William P. King   +5 more
doaj   +1 more source