Results 141 to 150 of about 52,263 (259)

Design, Scalable Synthesis, and Characterization of Poly(Oligourethane Methacrylate)s Bottlebrushes with Discrete, Sequence-Defined, and Stereocontrolled Side-Chains. [PDF]

Macromolecules
Mbizana S, Rutkowski J, Zwoliński K, Castellanos E, Pietrasik J, Szweda R.   +5 more
europepmc   +1 more source

Antimicrobial Cyclic Peptidomimetics

Macromolecular Rapid Communications, EarlyView.
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley   +1 more source

Regulatory Mechanisms of Lipid Rafts in Remodeling the Tumor Immune Microenvironment of Colorectal Cancer and Targeted Therapeutic Strategies. [PDF]

Biomolecules
Cheng Z, Gu J, Lu Y, Cai M, Zhang T, Wang J.   +5 more
europepmc   +1 more source

Arsonic Acid Functional Polymers Enable Stabilization of Iron Oxide Nanoparticles in Aqueous Solution

Macromolecular Rapid Communications, EarlyView.
Arsonic acid containing diblock copolymers are developed to incorporate arsonic acid moieties for surface anchoring to IONPs, along with water soluble PEG blocks to impart colloidal stability in aqueous environments. The resulting polymer‐coated IONPs are evaluated for stability in physiological media and cytocompatibility.
Nhu Thao Huynh, Alexander Rajakanthan, Jurie Tashkandi, Rafia Rafique, Milad Ghorbani, Zihnil A. I. Mazrad, Nicole M. Warne, Kiyonori Suzuki, Karen Alt, Paul Wilson, Kristian Kempe   +10 more
wiley   +1 more source

ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferring proteins for rapid ER export. [PDF]

Nat Commun
Castello-Serrano I, Dagar S, Ippolito R, Levental KR, Levental I.   +4 more
europepmc   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source

Targeting Cellular Lipid Rafts for Dynamic Nuclear Polarization Nuclear Magnetic Resonance. [PDF]

Chembiochem
Overall SA, Eck A, Wilson AT, Pinotsi D, Hartmann SJ, Packebusch K, Sigurdsson ST, Barnes AB.   +7 more
europepmc   +1 more source

Hydrogels Incorporating Donor–Acceptor Stenhouse Adducts as a Platform for Photoinduced, On‐Off Switchable Release of Small Molecule Cargos

Macromolecular Rapid Communications, EarlyView.
Donor–acceptor Stenhouse aDdducts (DASAs) are known for their photoinduced tautomerization, which, when conjugated to block copolymers, can self‐assemble into tuneable polymersomes. These DASA‐polymersomes are being investigated for light‐controlled cargo release in biomedical applications.
Tristan N. Dell, Ana Cammack‐Najera, Rea Tresa, Farzina Matubbar, Beyzanur Kaya, Uthaya Lathan, Mohamed Chami, Ray G. DiNardi, Omar Rifaie‐Graham, Jonathan P. Wojciechowski, Molly M. Stevens   +10 more
wiley   +1 more source

Charge-Shifting Copolymers of 2‑(<i>N</i>,<i>N</i>‑Dimethylamino)Ethyl Acrylate and 2‑Hydroxyethyl Acrylate via RAFT Polymerization: Balancing the Charge Content and Biological Response. [PDF]

ACS Appl Polym Mater
Sivkova R, Matiyani M, García-Briones GS, Konefal R, Lobaz V, Kotrchová L, Filová E, Podhorská N, Kostka L, Kubies D.   +9 more
europepmc   +1 more source

Active Learning for the Discovery of Antiviral Polymers

Macromolecular Rapid Communications, EarlyView.
Machine learning and active learning are integrated to accelerate the discovery of antiviral polymers. Molecular descriptors derived from polymer composition enable predictive modeling of antiviral activity, while unsupervised clustering explores chemical diversity. The active learning workflow identifies optimal candidates for synthesis, demonstrating
Clodagh M Boland, Nhat Quynh Nguyen, Nathan RB Boase   +2 more
wiley   +1 more source