Results 121 to 130 of about 276,241 (335)

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Oyster Reef Restoration Project for the City of Dover, Grizzle [PDF]

open access: yes, 2006
This project was conducted as a contract between the City of Dover and the University of New Hampshire, with additional funding supplied by the New Hampshire Estuaries Project.
Abeels, Holly   +2 more
core   +2 more sources

Loki, Io: New groundbased observations and a model describing the change from periodic overturn

open access: yes, 2006
Loki Patera is the most powerful volcano in the solar system. We have obtained measurements of Loki's 3.5 micron brightness from NASA's Infrared Telescope Facility (IRTF) and have witnessed a change from the periodic behavior previously noted. While Loki
Carr   +17 more
core   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

RAFT-mediated polymerization-induced self-assembly of poly(ionic liquid) block copolymers in a green solvent

open access: yese-Polymers
Synthesis of the poly(N,N-dimethylacrylamide)-b-poly(1-alkyl-3-(4-vinylbenzyl)imidazolium tetrafluoroborate) (PDMA43-b-PILx) block copolymers prepared by RAFT ethanol dispersion polymerization at 70°C.
Yang Yongqi   +7 more
doaj   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu   +8 more
wiley   +1 more source

Food allergy and mass catering: how to better accommodate allergic school children? Taking stock of an experience conducted in Franche-Comté region, France

open access: yesWorld Allergy Organization Journal, 2020
Laetitia Pellicer-Garcia   +5 more
doaj   +1 more source

Experimental and numerical study of piled raft system

open access: yes, 2016
Raft foundations are used when isolated footings cover more than 70% of the building area under a super structure. A combination between the use of piles and raft foundation is known as piled raft foundation.
A. Z. Elwakil, W. Azzam
semanticscholar   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

open access: yesAdvanced Science, EarlyView.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu   +23 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

open access: yesHepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol   +22 more
wiley   +1 more source

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