Results 111 to 120 of about 89,257 (292)

Enhancement of oral bioavailability of risedronate through xyloglucan rafts

Journal of Pharmacy & Pharmaceutical Sciences
Bisphosphonates irritate the stomach and oesophagus and have a very limited absorption. The purpose of this study was to increase risedronate (RDN) oral bioavailability by causing a raft to form in the stomach.
Nader I. Namazi, Rawan Bafail, Abdulkareem Ali Alanezi, Afaf F. Almuqati, Mohammed Salem Alshammari, Majed A. Alghamdi   +5 more
doaj   +1 more source

Light-induced modular ligation of conventional RAFT polymers

, 2013
Making light work of RAFT conjugation: A non-activated RAFT agent at the end of RAFT polymers can readily be coupled with ortho-quinodimethanes (photoenols) in a photo-triggered Diels-Alder reaction under mild conditions without catalyst (see scheme ...
Schmidt, F. G., Oehlenschlaeger, K. K., Heine, N. B., Guimard, N. K., Mueller, J. O., Delaittre, G., Barner-Kowollik, C., Glassner, M.   +7 more
core   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Degradable Alternating Copolymers With Strained Cyclobutane Backbones via Photocontrolled RAFT Polymerization

Angewandte Chemie, EarlyView.
A photocontrolled RAFT strategy enables the alternating copolymerization of 1,3‐disubstituted bicyclo[1.1.0]butanes with electron‐deficient comonomers, affording well‐defined copolymers bearing strained cyclobutane backbones. A high degree of alternation, tunable molecular weights, and excellent end‐group fidelity are achieved through a CTA‐mediated ...
Xia Hu, Hongsik Kim, Lianqian Wu, Yi Jiang, Tae‐Lim Choi   +4 more
wiley   +2 more sources

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Advanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao   +8 more
wiley   +1 more source

One‐Pot Synthesis of Aqueous PEDOT‐Based Conductive Inks via Sequential RAFT/Oxidative Polymerization

Angewandte Chemie, EarlyView.
We developed a fast, aqueous one‐pot synthesis for PEDOT:PSTFSI, combining sequential reversible addition–fragmentation chain‐transfer (RAFT) and oxidative polymerization. This method eliminates toxic solvents and purification steps, achieving full monomer conversion in under 3 h.
Fantine Negny, Melanie Bousquet, Benjamin Cabannes‐Boué, Pierre‐Yves Dugas, Lionel Hirsch, Thiago R. Guimaraes, Eric Cloutet   +6 more
wiley   +2 more sources

RAFT polymerization-induced self-assembly of poly(ionic liquids) in ethanol

e-Polymers, 2022
Yang Yongqi, Li Xiawei, Yan Youjun, Pan Rongkai, Liu Jun, Lian Meng, Luo Xin, Liu Guangyao   +7 more
doaj   +1 more source

Shallot cultivation in tropical climate ecosystems using floating and non-floating systems with different doses of cow manure

Advances in Horticultural Science
Deep swamp is swampland with the longest flooding period, making it challenging for crop cultivation. However, by adopting a floating system, this prolonged duration of flooding can be used for shallot growing.
Susilawati Susilawati, Irmawati Irmawati, Muhammad Umar Harun, Budiyati Ichwan   +3 more
doaj   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

Advanced NanoBiomed Research, EarlyView.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang, Liwei Liu, Jiayuan Zhu, Xinghao Hu, Changkui Fu, Yao Wang, Lining Arnold Ju, Thomas P. Davis, Andriansjah Rukmana, Shaohua Ma, Zheng Zhang, Ruirui Qiao   +11 more
wiley   +1 more source

Pathway Complexity Defines the Shape of Nucleic Acid‐Loaded Polyion Complex Micelles: Spheroids vs. Hexagonal Disks

Angewandte Chemie, EarlyView.
Same building blocks, different destinies. Pathway complexity directs nucleic acid–loaded polyion complex micelles along distinct assembly trajectories, resulting in either hexagonally shaped or spheroidal nanoparticles with distinct internal structuring.
Lennart van den Hoven, Neshat Moslehi, Eline F. Brink, Austin Hubley, Ilja K. Voets, Tina Vermonden, Elham Mirzahossein, Bas G. P. van Ravensteijn   +7 more
wiley   +2 more sources