Results 111 to 120 of about 276,241 (335)

Partition profile of the nicotinic acetylcholine receptor in lipid domains upon reconstitution[S]

open access: yesJournal of Lipid Research, 2010
The nicotinic acetylcholine receptor (AChR) is in intimate contact with the lipids in its native membrane. Here we analyze the possibility that it is the intrinsic properties of the AChR that determine its partition into a given lipid domain.
Vicente Bermúdez   +4 more
doaj   +1 more source

Nanoscopic substructures of raft-mimetic liquid-ordered membrane domains revealed by high-speed single-particle tracking

open access: yesScientific Reports, 2016
Lipid rafts are membrane nanodomains that facilitate important cell functions. Despite recent advances in identifying the biological significance of rafts, nature and regulation mechanism of rafts are largely unknown due to the difficulty of resolving ...
Hsiao-Mei Wu   +3 more
semanticscholar   +1 more source

Nitroxide‐Mediated Photo‐Polymerization: A Swiss Army Knife for Microfluidic Design

open access: yesAdvanced Materials Technologies, EarlyView.
This article illustrates the application of NMP2 to the rapid (less than 1 h) photostructuring and sealing of model structures intended for microfluidic applications. Remarkably, the careful design of resin composition allows completing these steps by simply spreading bare monomer (i.e., no added photoinitiator) on top of the bottom layer embedding ...
Carlo Gonzato   +5 more
wiley   +1 more source

Fundamentals of reversible addition–fragmentation chain transfer (RAFT)

open access: yesChemistry Teacher International, 2020
Radical polymerization is transformed into what is known as reversible addition–fragmentation chain transfer (RAFT) polymerization by the addition of a RAFT agent.
Moad Catherine L., Moad Graeme
doaj   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

open access: yesAdvanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu   +5 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Shiga Toxin—A Model for Glycolipid-Dependent and Lectin-Driven Endocytosis

open access: yesToxins, 2017
The cellular entry of the bacterial Shiga toxin and the related verotoxins has been scrutinized in quite some detail. This is due to their importance as a threat to human health.
Ludger Johannes
doaj   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

open access: yesAdvanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang   +9 more
wiley   +1 more source

Statistics of Bubble Rearrangements in a Slowly Sheared Two-dimensional Foam

open access: yes, 2004
Many physical systems exhibit plastic flow when subjected to slow steady shear. A unified picture of plastic flow is still lacking; however, there is an emerging theoretical understanding of such flows based on irreversible motions of the constituent ...
C. Macosko   +6 more
core   +1 more source

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

open access: yesJournal of Biological Chemistry, 2013
Background: Exosome vesicles can transfer molecular information previously shown to stimulate tumor development; however, the mechanism of exosome uptake is unknown.
Katrin J. Svensson   +7 more
semanticscholar   +1 more source

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