Results 101 to 110 of about 276,241 (335)

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

open access: yesCellular and Molecular Life Sciences, 2014
Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), a component of Gram-negative bacteria to induce production of pro-inflammatory mediators aiming at eradication of the bacteria. Dysregulation of the host responses to LPS can lead to a
Agnieszka Płóciennikowska   +3 more
semanticscholar   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Research on the Raft improved algorithm for anti-Byzantine nodes

open access: yes河南理工大学学报. 自然科学版
ObjectivesIn order to solve the problem of malicious election and log tampering caused by Byzantine nodes in original Raft algorithm, an AntiB-Raft (Anti-Byzantine Raft) algorithm was proposed to resist Byzantine nodes.MethodsWhen the candidate requested
WANG Xiaowei, LI Jie
doaj   +1 more source

Shear-Induced Stress Relaxation in a Two-Dimensional Wet Foam

open access: yes, 2002
We report on experimental measurements of the flow behavior of a wet, two-dimensional foam under conditions of slow, steady shear. The initial response of the foam is elastic. Above the yield strain, the foam begins to flow.
A. M. Kraynik   +14 more
core   +2 more sources

Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization [PDF]

open access: yes, 2017
En route towards improved delivery systems for targeted chemotherapy, we propose a straightforward approach for the hydrophobic modification of the acrylamide N-(2-Hydroxyethyl) acrylamide (HEAm).
De Geest, Bruno   +8 more
core   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen   +9 more
wiley   +1 more source

Reducing Settlement Using Piled Raft for Neighboring Foundations in Port-Said [PDF]

open access: yesPort Said Engineering Research Journal, 2013
The problems of building settlements in Port-Said area have been a great concern in recent years. Damages occur inbuildings due to urban development that requires high rise structures to accommodate these extensions.
doaj   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

open access: yesAdvanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long   +26 more
wiley   +1 more source

Structure-property relationships for polycarboxylate ether superplasticizers by means of RAFT polymerization

open access: yes, 2019
Hypothesis: Polycarboxylate ether (PCE) comb-copolymers are widely used as water reducing agents in the concrete industry while maintaining a high fluidity via the polymer adsorption to the cement particles.
De Schutter, Geert   +5 more
core   +1 more source

Catch, Release, Repeat: Reversible Protein Capture in Electric Fields Using Antifouling Polymer Brushes

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT Capturing proteins is easy since their amphiphilic nature allows them to bind to almost any surface. Because of this, releasing them is challenging since various interactions need to be considered for this. We present a simple method to reversibly adsorb proteins on stabilized electrodes.
Erik J. Postma   +3 more
wiley   +1 more source

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