Results 71 to 80 of about 51,172 (208)

Grafting polymer brushes from nylon surfaces <i>via</i> hydrogen atom transfer. [PDF]

open access: yesChem Sci
Ball TE   +8 more
europepmc   +1 more source

Artificial cell: An emerging bioactive material with advanced applications in cancer theranostics

open access: yesInterdisciplinary Medicine, EarlyView.
Artificial cells are emerging as attractive biomimetic bioactive materials that recapitulate key structures and functions of natural cells. This review systematically summarizes their major types, versatile fabrication strategies, tuneable properties and programmable biomimetic behaviours, highlights their cutting‐edge integrated applications in cancer
Daikun Wu, Shuo Yang, Hongjing Dou
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu   +6 more
wiley   +1 more source

Early deglaciation history of the southeastern Baffin Island shelf (Eastern Canadian Arctic Archipelago)

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT During the last glacial period, the Laurentide Ice Sheet (LIS) was the largest terrestrial ice sheet on Earth. Its evolution since the Last Glacial Maximum profoundly influenced Earth's geodynamics and surface processes. Investigating the past dynamics of the LIS provides critical insights into how contemporary ice sheets may respond to ...
Alexis P. Belko   +3 more
wiley   +1 more source

The Selective DHCR24 Blocker SH42 Inhibits ACE2 Binding and Cellular Entry of SARS-CoV-2 Spike Proteins More Efficiently Than Atorvastatin. [PDF]

open access: yesResearch (Wash D C)
Kovacs T   +10 more
europepmc   +1 more source

Marine Isotope Stage 4 glaciation in northern England, UK: Evidence from Victoria Cave, North Yorkshire

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT Victoria Cave, north Yorkshire, England, contains a long sequence of Pleistocene clastic sediments and calcite flowstones. Earlier work, using U–Th dating, established that the flowstone units formed in interglacial stages corresponding to Marine Isotope Stages (MIS) 13, 11, 9, 7 and 5.
Tom C. Lord   +7 more
wiley   +1 more source

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