One-carbon metabolism modulates miR-29a-DNA methylation crosstalk in Alzheimer's disease. [PDF]
Abstract INTRODUCTION Alzheimer's disease (AD)’s multifactorial nature stresses the role of epigenetics in affecting different pathological pathways. We demonstrated that one‐carbon metabolism epigenetically impacts AD‐like phenotype. Here, we investigated the crosstalk between methylation and microRNAs in AD.
Raia T +7 more
europepmc +2 more sources
Dose-Dependent Biphasic Effect of Palmitic Acid on Oligodendrocyte Function: Impacts on Viability, Differentiation, and Myelination. [PDF]
Schematic diagram showing dose‐dependent effects of PA in oligodendrocyte precursor MO3.13 cells and rodent organotypic hippocampal and cerebellar slice cultures. High doses lead to cell death accompanied by mitochondrial impairment, whereas low doses activate the Nrf2 antioxidant response and exert neuroprotective effect while balancing mitochondrial ...
Palmiero A +12 more
europepmc +2 more sources
Porcine Corneal Tissue and Xenozoonotic Risks: A Review of the Current Evidence. [PDF]
ABSTRACT Corneal opacities affect millions worldwide, with corneal transplantation as the primary treatment. However, donor shortages remain a challenge, leaving thousands waiting for transplants. Xenotransplantation using porcine corneas has emerged as a promising alternative due to anatomical and physiological similarities with human corneas ...
Moreira R +13 more
europepmc +2 more sources
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Brian Kendall +2 more
wiley +1 more source
Episodes of Molecular Emission in the Optical Spectrum of IRAS 22272+5435
Emission of carbon-bearing molecular lines in multiple optical spectra of IRAS 22272+5435 from 2015 to 2017 is detected, and, for the first time in post–asymptotic giant branch stars, real-time evolution of these features is observed. Specifically, lines
Kārlis Puķı̄tis +2 more
doaj +1 more source
Establishment and population expansion of the non-native Azores chromis (Chromis limbata) in the subtropical southwestern Atlantic. [PDF]
Abstract This study documents new records and the spatial–temporal progression of the non‐native Azores chromis (Chromis limbata) in southeastern Brazil, particularly on the coast of São Paulo state. We report the first confirmed occurrence of C. limbata in the Alcatrazes Archipelago and document that, in recent years, its abundance has exceeded that ...
Munhoz RR +5 more
europepmc +2 more sources
Background. Indole and polyamines are involved in the regulation of physiological processes in bacteria associated with adaptation to stress, biofilm formation, antibiotic tolerance, and bacterial persistence.
E. A. Khaova +2 more
doaj +1 more source
Aplicação do processo de secagem por liofilização em raia (Gymnura altavela)
O estímulo do consumo de pescado com base nas vantagens nutricionais e no efeito benéfico à saúde é limitado pela dificuldade em se encontrar no mercado um pescado de qualidade e de rápida manipulação/preparo.
Janaina de Paula da Costa +5 more
doaj +1 more source
Scabia – o dermatoză de actualitate în secolul XXI [PDF]
Scabia (râia) este o dermatoză comună parazitară cauzată de Sarcoptes scabiei. Este o boală contagioasă, cel mai adesea transmiterea se face prin contact direct sau indirect (ex: contactul cu lenjeria de pat, contactul sexual).
Ana Maria Alexandra Stănescu
doaj +1 more source
Католичке мисије и образовање у мултикултурном друштву – случај Солун
Рад прати утицаје различитих католичких мисионарских скупина од краја 17. и током 18. и 19. века на простору Балкана и Медитерана као реакцију против Реформације.
Raïa Zaïmova
doaj +1 more source

