Results 141 to 150 of about 2,084 (327)

Diverging in Vivo Immune Response Patterns After Oral Food Challenge in Peanut Allergic Adults

open access: yesClinical &Experimental Allergy, EarlyView.
After the oral food challenge, peanut (PN)‐allergic adults were monitored over 4 weeks, which revealed diverging immune response patterns, with strong responders (SR) exhibiting heightened Ara h 2+ B cell expansion, PN sIgE induction and increasing PN‐specific Tconv. Weak responders (WR) had more activated PN‐specific Tregs.
Florent Fauchère   +7 more
wiley   +1 more source

On the rainbow coloring for some graph operations

open access: yes, 2018
AIP Conference Proceedings 2016Let G = (V, E) be a nontrivial, finite, simple and undirected connected graph on which is defined a coloring f : E(G) → {1,2, …, k}, k ∈ N. The adjacent edges may be colored the same colors.
Alfarisi, Ridho   +3 more
core  

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

The Chromatic Spectrum of a Ramsey Mixed Hypergraph [PDF]

open access: yesComputer Science Journal of Moldova, 2016
We extend known structural theorems, primarily a result of Axenovich and Iverson, for the strict edge colorings of the complete graph $K_n$ which avoid monochromatic and rainbow triangles to discover recursive relationships between the chromatic spectra
David Slutzky, Vitaly Voloshin
doaj  

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

open access: yesThe FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek   +12 more
wiley   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

open access: yesThe FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan   +10 more
wiley   +1 more source

On the Rainbow Mean Indexes of Caterpillars

open access: yes, 2023
Let G be a simple connected graph and c an edge coloring with colors that are positive integers. Given a vertex v of G, we define its chromatic mean, denoted by cm(v), as the average of the colors of the incident edges. If cm(v) is an integer for each v ∈
Garciano, Agnes   +3 more
core  

Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70–Hsp110 chaperone system

open access: yesThe FEBS Journal, EarlyView.
Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff   +2 more
wiley   +1 more source

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