Results 171 to 180 of about 114,858 (292)

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1708-1726, March 2026.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat   +7 more
wiley   +1 more source

Evolution of lysine and arginine biosynthesis revealed by substrate specificity of lysine biosynthetic enzymes in Thermus thermophilus

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1727-1740, March 2026.
Two enzymes from the Thermus thermophilus lysine biosynthetic pathway, LysZ and LysY, unexpectedly exhibit substrate promiscuity. They are able to recognize the LysW intermediates utilized by the ArgW‐mediated arginine route, even though the bacterium already possesses the canonical arginine biosynthetic pathway.
Wenyuan Shi   +3 more
wiley   +1 more source

LPS-Induced Inflammation and Preconditioning in Rainbow Trout: Markers of Innate Immunity and Oxidative Stress. [PDF]

open access: yesAnimals (Basel)
Sukhovskaya IV   +7 more
europepmc   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1323-1340, March 2026.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim   +8 more
wiley   +1 more source

Novel TRIM Proteins Modulating the Innate Immune Response of Rainbow Trout (<i>Oncorhynchus mykiss</i>). [PDF]

open access: yesAnimals (Basel)
Donoso F   +9 more
europepmc   +1 more source

Binding of Bacillus subtilis dynamin‐like protein DynA to the bacterial membrane is essential for effective phage defense

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1741-1753, March 2026.
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat   +2 more
wiley   +1 more source

Correction: A novel high-throughput qPCR chip for solving co-infections in RAS farmed rainbow trout. [PDF]

open access: yesSci Rep
Sørensen J   +6 more
europepmc   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1754-1770, March 2026.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

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