Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: a phase I trial of bortezomib plus bevacizumab. [PDF]
PurposeWe hypothesized that bortezomib, an agent that suppresses HIF-1α transcriptional activity, when combined with bevacizumab, would obviate the HIF-1α resistance pathway.
Amin, Hesham M +16 more
core +9 more sources
The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer [PDF]
The significance of the inter-relationship between tumour and host local/systemic inflammatory responses in primary operable invasive breast cancer is limited.
A Ciucci +56 more
core +2 more sources
Vloga matičnih celic pri nastanku raka mlečne žleze
Rak mlečne žleze je najpogostejša oblika raka pri ženskah, zelo pogost pa je tudi pri nekaterih vrstah domačih živali (psi, mačke). Vse najnovejše raziskave s področja biologije mlečne žleze podpirajo hipotezo rakave matične celice, po kateri naj bi ...
Rok KEBER
doaj +1 more source
Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer [PDF]
This study identified LIMK2 kinase as a disease-specific target in castration resistant prostate cancer (CRPC) pathogenesis, which is upregulated in response to androgen deprivation therapy, the current standard of treatment for prostate cancer. Surgical
Broman, Meaghan M. +13 more
core +1 more source
Cancer event rate and mortality with thienopyridines: a systematic review and meta-analysis [PDF]
Introduction Thienopyridines are a class of antiplatelet drugs widely used in cardiovascular disease prevention and treatment. A recent concern has come to light regarding the safety of thienopyridines because of the possible risk of malignancy.
Kinnaird, T +5 more
core +2 more sources
Rak je drugi najvažniji uzrok smrti u našoj zemlji, odmah nakon bolesti srca i krvnih žila. S pretpostavkom porasta incidencije i smrtnosti od raka u idućim godinama, projekcije su da će se znatno povisiti i troškovi dijagnostike i liječenja raka, i zbog uvođenja novih dijagnostičkih tehnika i zbog inovativnih lijekova te metoda liječenja.
Šeparović, Robert +13 more
openaire +5 more sources
Combination of vinblastine and oncolytic herpes simplex virus vector expressing IL-12 therapy increases antitumor and antiangiogenic effects in prostate cancer models [PDF]
Oncolytic herpes simplex virus-1 (oHSV)–based vectors selectively replicate in tumor cells causing direct killing, ie., oncolysis, while sparing normal cells.
Cheema, Tooba +5 more
core +1 more source
Estrogen carcinogenesis in breast cancer [PDF]
Rak dojke je, uz rak pluća i rak debelog crijeva, najčešća i najsmrtonosnija vrsta raka koja pogađa uglavnom žensku populaciju razvijenih zemalja, osobito žene u menopauzi (iznad 50 godina).
Žarak, Martina
core +3 more sources
Ocena kadrovskih potreb za izvajanje zdravljenje raka v Republiki Sloveniji
Epidemiološki kazalci kažejo, daje rak v Sloveniji veliko javnozdravstveno breme. Rak je med vzroki smrti na prvem mestu pri moških in na drugem mestu pri ženskah.
Katarina Lokar +8 more
doaj
Putowski Maciej, Piróg Marta, Padała Olga, Piecewicz-Szczęsna Halina, Zukow Walery. Wybrane składniki diety w profilaktyce najczęściej występujących nowotworów w Polsce – przegląd aktualnych wyników badań = Selected components of the diet in the ...
Maciej Putowski +4 more
doaj +2 more sources

