Results 41 to 50 of about 513,363 (187)

Tissue factor in tumor microenvironment: a systematic review [PDF]

, 2014
The aberrant hemostasis is a common manifestation of cancer, and venous thromboembolism (VTE) is the second leading cause of cancer patients’ mortality.
Guo, Bo, Han, Xiao, Li, Yongsheng, Zhu, Bo   +3 more
core   +1 more source

Elevated Vascular Endothelial Growth Factor (VEGF) levels in the blood serum of dogs with malignant neoplasms of the oral cavity [PDF]

, 2014
Angiogenesis plays an essential role in the development of a neoplastic tumour by conditioning both its growth and the formation of metastases. The induction of blood vessel growth occurs under the influence of proangiogenic factors, among which Vascular
Polkowska, Izabela, Silmanowicz, Piotr, Sobczyńska-Rak, Aleksandra   +2 more
core   +1 more source

Carotenoids Modulate FoxO‐Induced Cell Cycle Arrest in Human Cancer Cell Lines: A Scoping Review

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
Carotenoids upregulated pro‐apoptotic and FoxO signalling clusters. Carotenoids downregulated PI3k/Akt signalling, TNF signalling and cell cycle regulation clusters. Carotenoids may induce cell cycle arrest via the FoxO signalling pathway. ABSTRACT Carotenoids, a class of antioxidants, have shown great potential for cancer management.
Zi Xin Lee, Hanting Guo, Aaron Deming Looi, Saatheeyavaane Bhuvanendran, Kasthuri Bai Magalingam, Wai Leng Lee, Ammu Kutty Radhakrishnan   +6 more
wiley   +1 more source

Epidemiologija raka debelega črevesa in danke

Onkologija, 2013
Debelo črevo in danka sta v zadnjih letih najpogostejše mesto (razen kože), na katerem pri prebivalstvu razvitega sveta, tudi v Sloveniji, nastane ena od rakavih bolezni. Za leto 2008 je ocenjeno, da je za rakom debelega črevesa in danke po svetu zbolelo
Maja Primic-Žakelj, Vesna Zadnik, Tina Žagar   +2 more
doaj  

Metastatis of cancer cells [PDF]

, 2013
Rak je bolest kod koje se tjelesne stanice nekotrolirano razmnožavaju zbog poremećenih normalnih regulacijskih mehanizama. Maligni tumori infiltriraju se u okolna tkiva prodirući među zdrave stanice i mogu se kroz krv i limfne žile proširiti na udaljene ...
Dodig, Helena
core   +2 more sources

Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration:disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling [PDF]

, 2016
The Notch ligand Jagged1 is subject to regulated intramembrane proteolysis (RIP) which yields a soluble ectodomain (sJag) and a soluble Jagged1 intracellular domain (JICD). The full-length Jagged1 protein enhances prostate cancer (PCa) cell proliferation
Brown, Mick, Clarke, Noel, Delury, Craig Phillip, Hart, Claire, Parkin, Edward Thomas   +4 more
core   +1 more source

Inhibition of Proliferation and Induction of Apoptosis by Gamma‐ or Delta‐Tocotrienols in Human Colorectal Carcinoma Cells

BioMed Research International, Volume 2025, Issue 1, 2025.
Colorectal cancer (CRC) remains a significant global health concern, necessitating the exploration of novel therapeutic approaches. This study investigated the anticancer effects of γ‐tocotrienol (γT3) and δ‐tocotrienol (δT3) on the human CRC cell lines HCC2998, HCT116, SW48 and Caco2.
Ali Qusay Khalid, Saatheeyavaane Bhuvanendran, Kasthuri Bai Magalingam, Premdass Ramdas, Ammu Kutty Radhakrishnan, Mohsin Khurshid   +5 more
wiley   +1 more source

PSA – biomarker, mis on muutnud eesnäärmehaiguste kliinilist käsitlust [PDF]

, 2009
Prostataspetsiifi line antigeen on enim kasutatav eesnäärmehaiguste marker kliinilises meditsiinis, mille tähtsus prostata biomarkerina avastati 1979. aastal. Oluline on teada, et PSA on eesnäärme-, mitte kasvajaspetsiifi line marker.
Ausmees, Kristo, Žarkovski, Mihhail
core   +2 more sources

AOP Report: An Upstream Network for Reduced Androgen Signaling Leading to Altered Gene Expression of Androgen Receptor–Responsive Genes in Target Tissues

Environmental Toxicology and Chemistry, Volume 43, Issue 11, Page 2329-2337, November 2024.
Abstract Adverse outcome pathways (AOPs) can aid with chemical risk assessment by providing plausible links between chemical activity at the molecular level and effect outcomes in intact organisms. Because AOPs can be used to infer causality between upstream and downstream events in toxicological pathways, the AOP framework can also facilitate ...
Monica K. Draskau, Anna K. Rosenmai, Nora Bouftas, Hanna K. L. Johansson, Eleftheria M. Panagiotou, Marie L. Holmer, Emilie Elmelund, Johanna Zilliacus, Anna Beronius, Pauliina Damdimopoulou, Majorie van Duursen, Terje Svingen   +11 more
wiley   +1 more source

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Al-Nedawi, Batagov, Bellingham, Bobrie, Bryant, Chen, Choi, Escrevente, Grady, Graner, Hood, Huang, Johnstone, Kim, King, Lai, Langmead, Li, Meyer, Mitchell, Mittelbrunn, Mortazavi, Muralidharan-Chari, Nilsson, Noerholm, Nolte-’t Hoen, Palma, Quinlan, Rabinowits, Raimondo, Raposo, Raposo, Ratajczak, Sandvig, Silva, Skog, Skokos, Taylor, Thorvaldsdottir, Valadi, Welton, Xing   +41 more
core   +1 more source