Results 61 to 70 of about 3,021 (161)

Unprecedented Nitrite‐Dependent Aromatic Amination to Synthesize 2,4‐Diamino‐3‐Hydroxybenzoic Acid

ChemBioChem, Volume 27, Issue 2, January 2026.
By comparing the biosynthetic gene clusters for natural products with 2,4‐diamino‐3‐hydroxybenzoic acid (2,4,3‐DAHBA) moiety and heterologous expression in Streptomyces albus, we identified nine genes required for the biosynthesis of 2,4,3‐DAHBA, including nitrite biosynthesis genes.
Ko Kuwabara, Yohei Katsuyama, Yasuo Ohnishi   +2 more
wiley   +1 more source

Biomanufacturing and Scale‐Up: Pathways to Biochemicals, Biofuels, and Biomaterials

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Carolina A. Barcelos, Pavel Dvořák, Charles J. Foster, Juan Nogales, Juan L. Ramos, Shamlan M. S. Reshamwala, Davinia Salvachúa   +6 more
wiley   +1 more source

Localising enzymes to biomolecular condensates increases their accumulation and benefits engineered metabolic pathway performance in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 171-186, January 2026.
Summary The establishment of Nicotiana benthamiana as a robust biofactory is complicated by issues such as product toxicity and proteolytic degradation of target proteins/introduced enzymes. Here we investigate whether biomolecular condensates can be used to address these problems. We engineered biomolecular condensates in N.
Anya L. Lindström Battle, Angus W. Barrett, Mark D. Fricker, Lee J. Sweetlove   +3 more
wiley   +1 more source

Diverse protein regulations on PHA formation in Ralstonia eutropha on short chain organic acids

International Journal of Biological Sciences, 2009
Organic acids are considered as potential substrates for biosynthesis of polyhydroxyalkaonates. The acids may also be the metabolic inhibitors at moderate concentration levels.
Sung-Eun Lee, Qing X. Li, Jian Yu
doaj  

A membrane‐bound [NiFe]‐hydrogenase large subunit precursor whose C‐terminal extension is not essential for cofactor incorporation but guarantees optimal maturation

MicrobiologyOpen, 2020
[NiFe]‐hydrogenases catalyze the reversible conversion of molecular hydrogen into protons end electrons. This reaction takes place at a NiFe(CN)2(CO) cofactor located in the large subunit of the bipartite hydrogenase module. The corresponding apo‐protein
Sven Hartmann, Stefan Frielingsdorf, Giorgio Caserta, Oliver Lenz   +3 more
doaj   +1 more source

Hybrid Modeling for Bioprocesses: Architectures, Applications, and Perspectives

Engineering Reports, Volume 7, Issue 12, December 2025.
This review analyzes 270 studies on hybrid semi‐parametric modeling in bioprocess engineering, highlighting dominant architectures, applications, and tools. It emphasizes the potential of hybrid models and process‐systems engineering to improve accuracy, extrapolation, and sustainability, aligning bioprocess development with key UN Sustainable ...
Juan Federico Herrera‐Ruiz, Javier Fontalvo, Oscar Andrés Prado‐Rubio   +2 more
wiley   +1 more source

Recent Progress in CO2 Conversion: An Overview of Catalytic Strategies for Sustainable Fuel and Chemical Synthesis

SmartMat, Volume 6, Issue 6, December 2025.
This review systematically outlines recent advances in the catalytic strategies for converting CO₂ into valuable products, including photocatalysis, electrocatalysis, CO2 hydrogenation, photothermal catalysis, non‐thermal plasma, and biocatalytic processes.
An Zhang, Yanming Cai, Liang Guo, Chao Wang, Qingbo Wa, Yanping Xu, Jian Zhou, Hongshuang Fan, Ziyun Li, Xinyue Long, Jiabei Tang, Zijian Li, Li Zhai, Zhenyu Shi, Wei Zhai, Yuhui Tian, Shuai Bi, Hao Wei, Mingliang Hu, Yang Xu, Yiran Zhang, Yu Zhang, Ruiying Ding, Junjun Li, Shuangqun Chen, Jianfeng Huang, Zhanxi Fan, Xingchen Jiao, Guigao Liu, Haiqing Wang, Haifeng Tian, Jingyu Pang, Kuncheng Zhang, Weisong Liu, Huijuan Cui, Lingling Zhang, Xiaofu Sun, Jianling Zhang, Dan Ren, Sheng Zhang, Lu Qiao, Zhe Weng, Hongmei Li, Min Liu, Miao Zhong, Lei Wang, Jun Gu, Hao Bin Wu, Bolong Huang, Weijia Zhou, Chuan Xia, Min‐Rui Gao, Changbin Zhang, Rong Cao, Wei Chen, Yuan‐Biao Huang, Yongye Liang, Ya‐Qian Lan, Guoxiong Wang, Baoyu Xia, Yujie Xiong, Xinbin Ma, Tongbu Lu, Jinhua Ye, Yi Xie, Buxing Han, Jiawei Liu, Zhicheng Zhang, Hua Zhang   +68 more
wiley   +1 more source

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

Advanced Science, Volume 12, Issue 44, November 27, 2025.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon, Eun‐Jung Kim, Hogyun Seo, Hyunjin Kim, Seungjin Shin, Caroline Schlaiß, Largus T. Angenent, Kyung‐Jin Kim, Byoung‐In Sang   +8 more
wiley   +1 more source

Current understanding of electroautotrophy and its relevance in astrobiology‐related research

mLife, Volume 4, Issue 5, Page 473-493, October 2025.
Abstract Electroautotrophy—the use of extracellular electrons as the primary energy source for autotrophic metabolism—remains understudied compared to photoautotrophy and chemoautotrophy. Its occurrence in deep‐earth and deep‐sea environments suggests profound implications for astrobiology, yet electroautotrophic microorganisms remain poorly explored ...
Quansheng Wang, Maggie C. Y. Lau Vetter
wiley   +1 more source

Production, optimization, scale up and characterization of polyhydoxyalkanoates copolymers utilizing dairy processing waste

Scientific Reports
The microbial biotransformation using low-cost feedstock to produce biopolymers (degradable), an alternative to petrochemical-based synthesis plastics (non-degradable), can be a beneficial approach towards sustainable development.
Tejaswini Dhanaji Patil, Saptaneel Ghosh, Aparna Agarwal, Sanjay Kumar Singh Patel, Abhishek Dutt Tripathi, Dipendra Kumar Mahato, Pradeep Kumar, Petr Slama, Ales Pavlik, Shafiul Haque   +9 more
doaj   +1 more source