Results 101 to 110 of about 21,216 (279)

Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

Viruses, 2015
Drug resistance prevents the successful treatment of HIV-positive individuals by decreasing viral sensitivity to a drug or a class of drugs. In addition to transmitted resistant viruses, treatment-naïve individuals can be confronted with the problem of ...
Thibault Mesplède, Mark A. Wainberg
doaj   +1 more source

Synthesis, molecular modeling and biological evaluation of two new chicoric acid analogs [PDF]

, 2016
Two conformationally constrained compounds similar to chicoric acid but lacking the catechol and carboxyl groups were prepared. In these analogues, the single bond between the two caffeoyl fragments has been replaced with a chiral oxirane ring and both ...
Bovicelli, P, Dallocchio, R, Dessì, A, Frezza, C, Isoni, V, Macchi, B, Pelagalli, R, Righi, G, Rossetti, I, Tirotta, I   +9 more
core   +1 more source

Raltegravir is the first HIV integrase inhibitor as part of antiretroviral treatment regimens

Терапевтический архив, 2010
The paper gives the results of the largest international studies demonstrating the efficacy and safety of Raltegravir as part of antiretroviral treatment (ARVT) regimens in both patients starting therapy (STARTMRK study) and those pretreated with ...
Aleksey Viktorovich Kravchenko, A V Kravchenko   +1 more
doaj  

Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models [PDF]

, 2016
To understand the persistence of latently HIV-1 infected cells in virally suppressed infected patients, a number of in vitro models of HIV latency have been developed.
Bonczkowski, Pawel, Borch, Alexandra, De Scheerder, Marie-Angélique, De Spiegelaere, Ward, Koenig, Renate, Malatinková, Eva, Melkova, Zora, Vandekerckhove, Linos   +7 more
core   +1 more source

Evaluation of cabotegravir plus rilpivirine in routine clinical settings in Japan: A multicentre study of efficacy, safety and biomarker dynamics

HIV Medicine, Volume 26, Issue 11, Page 1673-1683, November 2025.
Abstract Objectives Long‐acting cabotegravir plus rilpivirine (CAB+RPV) offers an alternative to daily oral therapy, but real‐world data in East Asia remain scarce. This study aims to evaluate the impact of CAB+RPV in people with HIV in Japan, focusing on virological outcomes, treatment continuation and inflammatory markers, providing valuable insight ...
Eisuke Adachi, Rumi Minami, Michinori Shirano, Hideta Nakamura, Kazuaki Fukushima, Mayumi Imahashi, Ryoko Sekiya, Yusuke Yoshino, Toshibumi Taniguchi, J‐HIV RWD Collaborative Database Team, Takashi Muramatsu, Yuji Hirai   +11 more
wiley   +1 more source

Brief Histories of Retroviral Integration Research and Associated International Conferences

Viruses
The field of retroviral integration research has a long history that started with the provirus hypothesis and subsequent discoveries of the retroviral reverse transcriptase and integrase enzymes.
Duane P. Grandgenett, Alan N. Engelman
doaj   +1 more source

Safety and efficacy of elvitegravir, dolutegravir, and raltegravir in a real-world cohort of treatment-naïve and -experienced patients

Medicine, 2019
Supplemental Digital Content is available in the ...
T. Brehm, Marleen Franz, A. Hüfner, S. Hertling, S. Schmiedel, O. Degen, B. Kreuels, J. Schulze zur Wiesch   +7 more
semanticscholar   +1 more source

Subgingival Bacterial Microbiota Profile of People Living With HIV‐1 Under HAART: A Systematic Review

Special Care in Dentistry, Volume 45, Issue 6, November/December 2025.
ABSTRACT Objective This systematic review aimed to assess the available literature on the subgingival bacterial microbiota profiles of PLHIV undergoing HAART. Materials and Methods This research was conducted in accordance with the PRISMA guidelines.
Tatiana Pinheiro de Macedo, Cristiane Gonçalves, Lucio Souza Gonçalves, Priscila Pereira Pavan Vidal, Josué da Costa Lima‐Junior, Mario Vianna Vettore, Rodrigo Carvalho de Souza   +6 more
wiley   +1 more source

Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen

Clinical Epidemiology, 2010
Frederik N Engsig1, Jan Gerstoft1, Gitte Kronborg2, Carsten S Larsen3, Gitte Pedersen4, Anne M Audelin5, Louise B Jørgensen5, Niels Obel11Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark; 2Department ...
Frederik N Engsig, Jan Gerstoft, Gitte Kronborg, et al   +3 more
doaj  

Erratum to: Body Composition Changes after Initiation of Raltegravir or Protease Inhibitors: ACTG A5260s [PDF]

, 2021

openalex   +1 more source