Results 131 to 140 of about 1,927 (159)
Einmal täglich Raltegravir funktioniert [PDF]
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Drugs, 2008
* Raltegravir, the first in a new class of orally administered HIV type-1 (HIV-1) integrase inhibitors, selectively inhibits the strand transfer activity of HIV-1 and its integration into human DNA, a key stage in retroviral propagation, thereby limiting viral replication and the infection of new cells.
Jamie D, Croxtall+2 more
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* Raltegravir, the first in a new class of orally administered HIV type-1 (HIV-1) integrase inhibitors, selectively inhibits the strand transfer activity of HIV-1 and its integration into human DNA, a key stage in retroviral propagation, thereby limiting viral replication and the infection of new cells.
Jamie D, Croxtall+2 more
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The Effect of Raltegravir on the Glucuronidation of Lamotrigine
The Journal of Clinical Pharmacology, 2009The authors studied the effect of raltegravir on the pharmacokinetics of the antiepileptic agent lamotrigine. Twelve healthy volunteers (group A) received 400 mg raltegravir twice daily from days 1 to 5. On day 4, a single dose of 100 mg lamotrigine was administered.
Luin, M. van+7 more
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Raltegravir-induced DRESS syndrome
Scandinavian Journal of Infectious Diseases, 2012DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is a life-threatening adverse drug reaction. Raltegravir is an integrase inhibitor used in HIV-1 infection. We report on a patient who developed a DRESS syndrome under raltegravir treatment, which was identified as a probable case of DRESS on the basis of Kardaun and Naranjo scores.
Olivier Mir, Pierre Loulergue
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Hospital Pharmacy, 2008
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to your Pharmacy & Therapeutics Committee. Subscribers also receive monthly 1-page summary monographs on the agents that are useful for agendas and pharmacy/
Dennis J. Cada+2 more
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Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to your Pharmacy & Therapeutics Committee. Subscribers also receive monthly 1-page summary monographs on the agents that are useful for agendas and pharmacy/
Dennis J. Cada+2 more
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Effect of Raltegravir on the Pharmacokinetics of Methadone
The Journal of Clinical Pharmacology, 2010A randomized, placebo‐controlled, 2‐period crossover study in subjects on methadone maintenance therapy was conducted to assess the effect of the HIV‐1 integrase inhibitor, raltegravir, on the pharmacokinetics of methadone. Twelve HIV‐negative male and female subjects stabilized on an oral methadone program were enrolled.
Julie Ann Mabalot Luk+8 more
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