Results 151 to 159 of about 1,927 (159)

Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure

Antiviral Research, 2010
Using quantitative deep HIV-1 sequencing in a subject who developed virological failure to deep salvage therapy with raltegravir, we found that most Q148R and N155H mutants detected at the time of virological failure originated from pre-existing minority Q148R and N155H variants through independent evolutionary clusters.
Rafael Delgado, Alexander Thielen, Roger Paredes, Federico García, Maria J. Buzon, Lidia Ruiz, Bonaventura Clotet, José R. Santos, Javier Martinez-Picado, Christian Pou, Francisco M. Codoñer, David Dalmau, Miguel Álvarez-Tejado   +12 more
openaire   +4 more sources

Clinical Use of Raltegravir: A Review

HIV Therapy, 2010
In the last 5 years there have been important achievements in the field of HIV therapy with the availability of new classes of antiretrovirals together with a new generation of old classes. Among them, the development of raltegravir, the first commercially available component of integrase inhibitors, brought an extraordinary improvement in salvage ...
Beatriz Grinsztejn, Estevão Portela Nunes, Marilia Santini de Oliveira   +2 more
openaire   +2 more sources

Variability of Raltegravir Plasma Levels in the Clinical Setting

Pharmacology, 2013
Therapeutic drug monitoring of raltegravir C_trough levels was carried out in the setting of the Raltegravir Switch for Toxicity or Adverse events (RASTA) trial, a randomized pilot study exploring a 48-week safety and efficacy of treatment switch to raltegravir associated with tenofovir/emtricitabine or abacavir/lamivudine in ...
Fortuna, Serena, Fabbiani, Massimiliano, Di Giambenedetto, Simona, Ragazzoni, Enzo, Lisi, Lucia, Cauda, Roberto, Navarra, Pierluigi   +6 more
openaire   +4 more sources

Elvitegravir: a once daily alternative to raltegravir

The Lancet Infectious Diseases, 2012
Rik Schrijvers, Zeger Debyser, Belete Ayele Desimmie   +2 more
openaire   +3 more sources

Raltegravir and rifampicin in patients with HIV and tuberculosis

The Lancet Infectious Diseases, 2014
Wouter F W Bierman, Annelies Riezebos-Brilman   +1 more
openaire   +6 more sources

Dosing of raltegravir when given with rifampicin

The Lancet Infectious Diseases, 2014
Graeme Meintjes, Graeme Meintjes, Gary Maartens   +2 more
openaire   +3 more sources

164 An update on raltegravir (Isentress)

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2009
openaire   +2 more sources

New drugs: Doripenem, Raltegravir, And Ixabepilone

Journal of the American Pharmacists Association, 2008
openaire   +3 more sources

Raltegravir — ein guter Kombinationspartner

MMW - Fortschritte der Medizin, 2015
openaire   +2 more sources