Spectrophotometric estimation of raltegravir potassium in tablets.
Indian journal of pharmaceutical sciences, 2014 Ultra violet spectrophotometric estimation of the raltegravir potassium, an integrase inhibitor antiretroviral agent was estimated by Ultra violet absorption maxima method at λmax of 328 nm and UV area under curve method in the wave length range of 323-333 nm.
KG Baheti +3 more
openaire +4 more sources
Fluorspar to fluorochemicals upon low-temperature activation in water. [PDF]
NatureThe dangerous chemical hydrogen fluoride sits at the apex of the fluorochemical industry, but the substantial hazards linked to its production under harsh conditions (above 300 degrees Celsius) and transport are typically contracted to specialists.
Klose I +5 more
europepmc +3 more sources
Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivatives [PDF]
, 2020 N-Hydroxy-4-oxoquinazoline-2-carboxamide derivatives (cyclic hydroxamic acids) and related pyrido- and thieno-substituted analogues, as well as a N-hydroxyhypoxanthine-2-carboxamide were synthesised for the first time, by means of a four-step sequence ...
Bosch Hereu, Lluís +3 more
core +1 more source
Standard-dose versus double-dose dolutegravir in HIV-associated tuberculosis in South Africa (RADIANT-TB): a phase 2, non-comparative, randomised controlled trial [PDF]
, 2023 Background: The drug–drug interaction between rifampicin and dolutegravir can be overcome by supplemental dolutegravir dosing, which is difficult to implement in high-burden settings.
Griesel, Rulan +8 more
core +2 more sources
Global testing of a consensus solubility assessment to enhance robustness of the WHO biopharmaceutical classification system [PDF]
, 2020 The WHO Biopharmaceutical Classification System (BCS) is a practical tool to identify active pharmaceutical ingredients (APIs) that scientifically qualify for a waiver of in vivo bioequivalence studies.
Anita Wessels +12 more
core +2 more sources
The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo [PDF]
, 2021 Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. Serrated adenocarcinoma (SAC) has been recently recognized by the WHO as a histological CRC with bad prognosis. Consistent with previous evidence, our group identified
Alburquerque-Gonzá +14 more
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Rhabdomyolysis in an HIV cohort: epidemiology, causes and outcomes. [PDF]
, 2017 BackgroundThe Literature on rhabdomyolysis in the HIV-positive population is sparse and limited. We aimed to explore the incidence, patient characteristics, etiologies and outcomes of rhabdomyolysis in a cohort of HIV-positive patients identified through
Atta, Mohamed G +6 more
core +1 more source
Analysis of in vivo absorption of didanosine tablets in male adult dogs by HPLC [PDF]
, 2012 Didanosine is an effective antiviral drug in untreated and antiretroviral therapy-experienced patients with Human Immunodeficiency Virus (HIV). An automated system using on-line solid extraction and High Performance Liquid Chromatography (HPLC) with ...
Dalla Costa, Teresa Cristina T. +4 more
core +2 more sources
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANIOUS ESTIMATION AND FORCED DEGRADATION STUDIES OF LAMIVUDINE AND RALTEGRAVIR IN SOLID DOSAGE FORM [PDF]
, 2018 Objective: A stability indicating reverse phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the estimation of the combined tablet formulation of lamivudine (LAM) and raltegravir (RAL) in dosage forms and its ...
Rajan, R. Govinda +1 more
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HIV, hepatitis B and hepatitis C coinfection in Kenya [PDF]
, 2008 There are few data regarding hepatitis and HIV coinfection in Africa. In 378 HIV seropositive individuals in Nairobi, 23 (6%) were hepatitis B virus (HBV) and HIV coinfected, four (1%) were hepatitis C virus (HCV) and HIV coinfected and one patient was ...
Karuru, Jane +3 more
core +2 more sources