Improved Automated Radiosynthesis of [18F]Dolutegravir: Toward Clinical Applications. [PDF]
Huvelle S+9 more
europepmc +1 more source
Amiodarone Therapy: Updated Practical Insights. [PDF]
Șorodoc V+9 more
europepmc +1 more source
Advances in humanoid organoid-based research on inter-organ communications during cardiac organogenesis and cardiovascular diseases. [PDF]
Ni B, Ye L, Zhang Y, Hu S, Lei W.
europepmc +1 more source
N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants. [PDF]
Mahajan PS+6 more
europepmc +1 more source
In Vitro Anti-HIV-1 Activity of Fucoidans from Brown Algae. [PDF]
Nosik MN+7 more
europepmc +1 more source
Immunological Enigma: A Case Report of COVID-19 Survival in a Patient With Human Immunodeficiency Virus, Hepatitis C Virus, and Tuberculosis Co-infection. [PDF]
Bozhkova M+4 more
europepmc +1 more source
Acute promyelocytic leukemia with additional chromosome abnormalities in a patient positive for HIV: A case report and literature review. [PDF]
Li XL+5 more
europepmc +1 more source
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to your Pharmacy & Therapeutics Committee. Subscribers also receive monthly 1-page summary monographs on the agents that are useful for agendas and pharmacy/
Dennis J. Cada+2 more
semanticscholar +4 more sources
A Facile Synthesis of Raltegravir Potassium—An HIV Integrase Inhibitor
A facile, cost‐effective, and commercially viable synthesis of Raltegravir Potassium (1) has been developed from 2‐(1‐amino‐1‐methyl‐ethyl)‐N‐[(4‐fluorophenyl)methyl]‐1,6‐dihydro‐5‐hydroxy‐1‐methyl‐6‐oxo‐4‐pyrimidinecarboxamide (9) with high purity and in good yields.
Kishore Karumanchi+5 more
semanticscholar +4 more sources
Multiple sources of anticipated degradation and process impurities of raltegravir potassium drug substance observed during the laboratory optimization and later during its bulk synthesis are described in this article. The impurities were monitored by UPLC, and their structures are tentatively assigned on the basis of fragmentation patterns in LC–MS and
Gulabrao D. Patil+8 more
semanticscholar +4 more sources