Results 31 to 40 of about 492,703 (122)
, 2021 Aims: To evaluate the efficacy, effectiveness, and safety of integrase inhibitors in the treatment of HIV/AIDS in patients coinfected with tuberculosis (TB). Methods: Clinical trials or observational studies were included.
N. Resende +5 more
semanticscholar +1 more source
Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]
, 2015 Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W +6 more
core +2 more sources
Risks and benefits HIV preexposure prophylaxis with tenofovir/emtricitabine in an older male with comorbidities [PDF]
, 2016 Renal toxicity in a 73 year old man using tenofovir/emtricitabine (TDF/FTC) as pre-exposure prophylaxis (PrEP) is described. Reduced renal reserve, a higher exposure to co-medications and co-morbidities can present a challenge when assessing the risks ...
Barber, TJ +5 more
core +1 more source
A Randomized Trial of Dolutegravir Plus Darunavir/ Cobicistat as a Switch Strategy in HIV-1-Infected Patients With Resistance to at Least 2 Antiretroviral Classes [PDF]
, 2023 Suppressed patients with drug-resistant HIV-1 require effective and simple antiretroviral therapy to maintain treatment adherence and viral suppression. This randomized, open-label, noninferiority, multicenter pilot study involved HIV-infected adults who
Bernal, Enrique +16 more
core +1 more source
Cellular Active N-Hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site [PDF]
, 2016 The structure-specific nuclease human flap endonuclease-1 (hFEN1) plays a key role in DNA replication and repair and may be of interest as an oncology target. We present the first crystal structure of inhibitor-bound hFEN1 and show a cyclic N-hydroxyurea
A Desai +68 more
core +2 more sources
Standard-dose versus double-dose dolutegravir in HIV-associated tuberculosis in South Africa (RADIANT-TB): a phase 2, non-comparative, randomised controlled trial [PDF]
, 2023 Background: The drug–drug interaction between rifampicin and dolutegravir can be overcome by supplemental dolutegravir dosing, which is difficult to implement in high-burden settings.
Griesel, Rulan +8 more
core +2 more sources
AIDS (London), 2022 Objective: To study gut microbiota before and 24 weeks after a single antiretroviral agent switch. Design: HIV-positive patients with efavirenz (EFV) or a protease inhibitor (PI)-based antiretroviral therapy (ART) were randomized to switch EFV or PI to ...
A. Hanttu +6 more
semanticscholar +1 more source
Burkitt Lymphoma of the Duodenum: An Uncommon Phenomenon
Case Reports in Gastrointestinal Medicine, Volume 2019, Issue 1, 2019., 2019 Burkitt lymphoma is an aggressively growing tumor commonly found in African children, involving the jaw and facial bones. Most non‐Hodgkin lymphoma tumors involve extra nodal sites like the nervous system and gastrointestinal tract. A rare variant of this type of lymphoma is found in immunocompromised patients specifically in the gastrointestinal tract
Fahad Malik +3 more
wiley +1 more source
HIV, hepatitis B and hepatitis C coinfection in Kenya [PDF]
, 2008 There are few data regarding hepatitis and HIV coinfection in Africa. In 378 HIV seropositive individuals in Nairobi, 23 (6%) were hepatitis B virus (HBV) and HIV coinfected, four (1%) were hepatitis C virus (HCV) and HIV coinfected and one patient was ...
Karuru, Jane +3 more
core +2 more sources
Case Reports in Nephrology, Volume 2017, Issue 1, 2017., 2017 Peritoneal dialysis (PD) has recently been established as a treatment option for renal replacement therapy (RRT) in patients with acute kidney injury (AKI). Its efficacy in providing fluid and small solute removal has also been demonstrated in clinical trials and is equivalent to hemodialysis (HD).
Donlawat Saengpanit +4 more
wiley +1 more source