Results 31 to 40 of about 1,533 (110)

Episodic fevers and vasodilatory shock mimicking urosepsis in a patient with HIV-associated multicentric Castleman’s Disease: a case report [PDF]

, 2016
Background: Multicentric Castleman's disease (MCD) is a pre-malignancy that presents with lymphadenopathy and features of systemic inflammation. Human immunodeficiency virus (HIV)-associated MCD is associated with human herpesvirus-8 (HHV-8) infection ...
Frederick J. Lee, Roger Garsia, Sarah C. Sasson, Stephanie Anderson, Stephen Larsen, Wendy Cooper   +5 more
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Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection [PDF]

, 2010
Understanding the pharmacokinetics of drugs in peripheral body compartments, such as the genital tract, is particularly important in the infectious diseases arena.
Kashuba, Angela D.M., Rezk, Naser L., Talameh, Jasmine A.   +2 more
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Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction [PDF]

Though much progress has been made in the inhibition of HIV-1 integrase catalysis, clinical resistance mutations have limited the promise of long-term drug prescription. Consequently, allosteric inhibition of integrase activity has emerged as a promising
Christ, Frauke, Debnath, Bikash, Debyser, Zeger, Long, Ya-Qiu, Neamati, Nouri, Serrao, Erik, Xu, Zhong-Liang   +6 more
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A multisystem investigation of raltegravir association with intestinal tissue: implications for pre-exposure prophylaxis and eradication [PDF]

, 2014
ObjectivesRecent clinical data have suggested high raltegravir concentrations in gut tissue after oral administration, with implications for treatment and prevention. We have used in silico, in vitro, ex vivo and in vivo models to further investigate the

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Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients [PDF]

, 2013
Viral genotype assessment is important for effective clinical management of HIV-1 infected patients, especially when access and/or adherence to antiretroviral treatment is reduced.
Folk, W.R., Gatanaga, H., Hachiya, A., Hong, S.P., Kim, S.-O., Kirby, K.A., Lee, J., Lee, J.-H., Oka, S., Ong, Y.T., Sarafianos, S.G., Shin, S.-K., Yoo, W.   +12 more
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Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation [PDF]

, 2017
HIV-1 integrates more frequently into transcribed genes, however the biological significance of HIV-1 integration targeting has remained elusive. Using a selective high-throughput chemical screen, we discovered that the cardiac glycoside digoxin inhibits
Ancuta, Petronela, Anderson, Ian, Bangham, Charles R M, Fassati, Ariberto, Ketteler, Robin, Kriston-Vizi, Janos, Lee, Abraham, Melamed, Anat, Merritt, Andy, Planas, Delphine, Routy, Jean-Pierre, Zhyvoloup, Alexander   +11 more
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Guidelines for antiretroviral therapy in adults [PDF]

, 2012
These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in January 2008. Since the release of the previous guidelines, the scaleup of antiretroviral therapy (ART) in Southern Africa has continued to ...
G Maartens, G Meintjes
core   +3 more sources

An accurate and precise high-performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction [PDF]

, 2008
The quantification of the HIV integrase inhibitor raltegravir in blood plasma is described using solid phase extraction (SPE) coupled with an accurate high-performance liquid chromatography assay with ultraviolet (UV) detection.
Kashuba, Angela D.M., Rezk, Naser L., White, Nicole   +2 more
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A Comparative Study of Newly Developed HPLC-DAD and UHPLC-UV Assays for the Determination of Posaconazole in Bulk Powder and Suspension Dosage Form [PDF]

, 2014
Objective. To develop and compare HPLC-DAD and UHPLC-UV assays for the quantitation of posaconazole in bulk powder and suspension dosage form. Methods. Posaconazole linearity range was 5–50 μg/mL for both assays. For HPLC-DAD assay, samples were injected
Dalia A. Hamdy, Tarek S. Belal
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Bio-analytical Assay Methods used in Therapeutic Drug Monitoring of Antiretroviral Drugs-A Review [PDF]

, 2019
Background: Several clinical trials, as well as observational statistics, have exhibited that the advantages of antiretroviral [ARV] treatment for humans with Human Immunodeficiency Virus / Acquired Immune Deficiency Syndrome HIV/AIDS exceed their risks.
Abdissa A., Abobo C.V., Akeb F., Alsenz J., Amad M.H., Amara A.B., Aouri M., Armbruster C., Arts E.J., Arts E.J., Avery L.B., Avihingsanon A., Avolio A.D., Aymard G., Aymard G., Azoulay S., B. Ramesh, Ballantyne A.D., Barkil M.E., Barone G.C., Barone G.C., Bastiani E., Becher F., Bennetto-hood C., Bienvenu E., Bloom J., Boffito M., Bossi P., Brereton R.G., Brewer E., Brown S.D., Burger D., Burger D.M., Burhenne J., Burugula L., Busti A.J., Campanero M., Campbell T.B., Castellino S., Castro A.A., Cateau E., Cattaneo D., Chan C.P., Chang D., Chapman T., Charbe N., Cheeseman S.H., Chen R.Y., Chi B., Chi J., Chi J., Chittick G.E., Choi S.O., Clark T.N., Clevenbergh P., Clumeck N., Cohen C., Colombo S., Colombo S., Colombo S., Cottrell M.L., Coulier L., Cozzi V., Cozzi V., Crauwels H., Crommentuyn K.M., Crommentuyn K.M., Custodio J.M., Dailly E., Dailly E., Dailly E., Dando T.M., Darque A., Das Mishra T., De Meyer S., Deeks E.D., DeJesus E., Delahunty T., Dickinson L., DiFrancesco R., Djerada Z., Dong M.W., Dorr P., Douglas D.J., Dunge A., D’Avolio A., D’Avolio A., D’Avolio A., D’Avolio A., D’Avolio A., Eagling V.A., Eichhorst J.C., Elens L., Elens L., Elens L., Else L., Emilio Clementi, Eron J.J., Estrela R.C., Estrela Rde C., Faletto M.B., Fan B., Fayet A., Fayet A., Ferrer S.M., Findlay J.W., Fitzsimmons M.E., Fizzano M.R., Flavia C. Zacconi, Fletcher C.V., Flexner C., Foldes O., Ford N., Foster R.H., Fraaij P.L., Frappier S., Friedland G., Fung E.N., Gallant J.E., Gervasoni C., Giraud E., Goldwirt L., Goldwirt L., Gomes N.A., Granda B.W., Granich G.G., Grix R., Grégoire M., Gupta A., Gupta A., Ha H.R., Haqqani A.A., Harker A.J., Havlir D., Hirabayashi Y., Hirano A., Hoetelmans R.M., Hoetelmans R.M., Hoffman J.T., Hollanders R.M., Hsu A., Hsu A., Hsyu P.H., Hurst M., Hurwitz S.J., Hwang H., Hyland R., Ibbotson T., Ishikawa T., Janoly A., Jansen R.S., Jayewardene A.L., Jemal M., Jourdil J.F., Jullien V., Jung B.H., Justesen U.S., Justesen U.S., Kabra V., Kakuda T.N., Kang J.S., Kassahun K., Kearney B.P., Keil K., Kenney K.B., Kilby J.M., Kim A.E., King J.R., King T., Klecker R.W., Klibanov O.M., Knebel N.G., Knebel N.G., Koal T., Koal T., Koh Y., Koteff J., Kromdijk W., Kromdijk W., Kumar P.N., Kupferschmidt H.H., La Porte C.J., Lamotte C., Langmann P., Langmann P., Langmann P., Lau G.K., Laurito T.L., Lawless M.K., Lawrence C.C., Le Saux T., Lea A.P., Lee L.L., Leibenguth P., Leschziner G.D., Letendre S., Lewis S.R., Lillibridge J.H., Liu Z., Long M.C., Loregian A., Maganda B., Maggiolo F., Manzardo C., Marsh K.C., Martin J., Marzinke M.A., Marzolini C., Marzolini C., Mathias A.A., Matta M.K., Matthews C.Z., McDowell J.A., Mcdowell J.A., McIlleron H.M., Meesters R.J., Merry C., Merschman S.A., Mills E.J., Mocroft A., Mogatle S., Molina J.M., Moody W., Moss D.M., Moyer T.P., Murphy R.L., Murphy R.L., Murtaza M. Tambuwala, Myasein F., Müller A.C., Nadal T., Nandi U., Naxing Xu R., Nettles R.E., Nikhil Amnerkar, Nirogi R., Nirogi R., Nitin B. Charbe, Notari S, Notari S., Notari S., Notari S., Ostrowski M.A., Pav J.W., Pedersen O.S., Penzak S.R., Pereira A.S., Pereira A.S., Peris-vicente J., Perry C.M., Perry C.M., Piscitelli S.C., Plumb R.S., Podany A.T., Poirier J., Poirier J.M., Polk R.E., Polli J.W., Pommier Y., Profit L., Proust V., Pruvost A., Pynnönen S.T., Quaranta S., Quevedo M.A., Rakhmanina N.Y., Ramachandran G., Ramanathan S., Ramanathan S., Raviolo M.A., Ravitch J.R., Ray J., Reese M.J., Remmel R.P., Rentsch K.M., Rezk N.L., Rezk N.L., Rezk N.L., Rezk N.L., Rezk N.L., Rezk N.L., Rezk N.L., Ribera E., Robbins B.L., Robbins B.L., Robbins B.L., Rotty J., Rouzes A., Rower J.E., Sadler B.M., Santoscoy M., Saras-Nacenta M., Sarasa-Nacenta M., Schinkel A.H., Schuster A., Schöller-Gyüre M., Sekar V.J., Sentenac S., Seshachalam U., Shah B.M., Shehu-Xhilaga M., Shibata M., Shimura K., Silverthorn C.F., Simiele M., Simon V.A., Solas C., Somboonwit C., Song I., Song I., Sparidans R.W., Sparidans R.W., Sparidans R.W., Sparidans R.W., Stefan R.I., Stoiber H., Svensson J.O., Takahashi M., Takahashi M., Talameh J.A., Tan X., Tarinas A., Temesgen Z., Ter Heine R., Ter Heine R., Ter Heine R., Ter Heine R., Ter Heine R., Ter Heine R., Tilton J.C., Titier K., Tribut O., Tribut O., Trnková L., Turner M.L., Ucpinar S.D., Uglietti A., Usami Y., Uslu B., Van Heeswijk R., Van Heeswijk R.P., Van Heeswijk R.P., Van Heeswijk R.P., Veal G.J., Veldkamp A.I., Veldkamp A.I., Verbesselt R., Verma S., Vermeir M., Verweij-van W.C.P., Villani P., Villani P., Vogel M., Volosov A., Vourvahis M., Walker D.K., Walmsley S.L., Wang L.H., Wang P.G., Watanabe K., Wattananat T., Weller D.R., Weller S., Williams D.I., Wiltshire H.R., Wood R., Woolf E., Wu E.Y., Yadav M., Yadav M., Yilmaz A., Yuen G.J., Zhang J., Zheng W., Zhou X.J.   +374 more
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