Results 41 to 50 of about 492,703 (122)

Coexistent Pseudogout and Mycobacterium avium-intracellulare Septic Arthritis in a Patient with HIV and ESRD

Case Reports in Rheumatology, Volume 2016, Issue 1, 2016., 2016
Pseudogout is a crystal‐induced arthropathy characterized by the deposition of calcium pyrophosphate dihydrate (CPPD) crystals in synovial fluid, menisci, or articular cartilage. Although not very common, this entity can be seen in patients with chronic kidney disease (CKD).
Wais Afzal, Omer M. Wali, Kelly L. Cervellione, Bhupinder B. Singh, Farshad Bagheri, Jamal Mikdashi   +5 more
wiley   +1 more source

N-4 Alkyl cytosine derivatives synthesis: a new approach [PDF]

, 2022
The selective N-4 alkylation of cytosine plays a critical role in the synthesis of biologically active molecules. This work focuses on the development of practical reaction conditions toward a regioselective synthesis of N-4-alkyl cytosine derivatives.
Alessia Bertamino, Antonio Di Maio, Carmine Ostacolo, Isabel M. Gomez-Monterrey, Mauro De Nisco, Michele Manfra, Pietro Campiglia, Silvana Pedatella   +7 more
core   +3 more sources

Nutritional Supplementation with the Mushroom Agaricus sylvaticus Reduces Oxidative Stress in Children with HIV

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 25, Issue 5, Page 257-264, 2014., 2014
BACKGROUND: The involvement of free radicals and oxidative stress in HIV infection has been extensively studied, and the benefits of antioxidant supplementation in animal studies have been demonstrated. However, few studies have demonstrated a benefit in clinical studies.
Marcela S Figueira, Luana A Sá, Amanda S Vasconcelos, Danilo R Moreira, Paula SOC Laurindo, Danielle RG Ribeiro, Rogério S Santos, Paulo Guzzo, Maria F Dolabela, Sandro Percario   +9 more
wiley   +1 more source

Raltegravir in second-line antiretroviral therapy in resource-limited settings (SELECT): a randomised, phase 3, non-inferiority study [PDF]

, 2016
For second-line antiretroviral therapy, WHO recommends a boosted protease inhibitor plus nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs).
Collier, Ann C, Harrison, Linda J, Hosseinipour, Mina C, Jarocki, Bernadette, Kim, Peter, Kumarasamy, Nagalingeswaran, La Rosa, Alberto M, Mellors, John W, Taiwo, Babafemi, Wallis, Carole L, Zheng, Lu   +10 more
core   +2 more sources

Iatrogenic Cushing Syndrome Secondary to Ritonavir‐Epidural Triamcinolone Interaction: An Illustrative Case and Review

Interdisciplinary Perspectives on Infectious Diseases, Volume 2014, Issue 1, 2014., 2014
HIV positive patients on ritonavir‐containing antiretroviral therapy (ART) can develop iatrogenic Cushing syndrome (IACS) and adrenal insufficiency as a result of drug‐drug interactions with inhaled or intranasal glucocorticoid therapy. Reports related to epidural triamcinolone injections are relatively uncommon but increasingly reported. We describe a
Sapna Sadarangani, Melody L. Berg, William Mauck, Stacey Rizza, Sandro Cinti   +4 more
wiley   +1 more source

8-modified-2\u27-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription [PDF]

, 2011
The occurrence of resistant viruses to any of the anti-HIV-1 compounds used in the current therapies against AIDS underlies the urge for the development of new drug targets and/or new drugs acting through novel mechanisms. While all anti-HIV-1 nucleoside
Alain Burger, Anne-Marie Aubertin, Catherine Isel, Guillaume Bec, Géraldine Laumond, Jean-Pierre Vartanian, Johnson Mak, Marwan Sleiman, Matthias Götte, Nouha Ben Gaied, Patrick Barhoum, Redmond Smyth, Roland Marquet, Valérie Vivet-Boudou   +13 more
core   +4 more sources

Serum creatine kinase elevation following tyrosine kinase inhibitor treatment in cancer patients: Symptoms, mechanism, and clinical management

Clinical and Translational Science, Volume 17, Issue 11, November 2024.
Abstract Molecular targeted tyrosine kinase inhibitors (TKIs) have produced unprecedented treatment response in cancer therapy for patients harboring specific oncogenic mutations. While the TKIs are mostly well tolerated, they were reported to increase serum levels of creatine kinase (CK) and cause muscle metabolism‐related toxicity. CK is an essential
Hang Zhang, Kenneth K. W. To
wiley   +1 more source

Duodenal Histoplasmosis Presenting with Upper Gastrointestinal Bleeding in an AIDS Patient

Case Reports in Gastrointestinal Medicine, Volume 2012, Issue 1, 2012., 2012
Gastrointestinal histoplasmosis (GIH) is common in patients with disseminated disease but only rarely comes to clinical attention due to the lack of specific signs and symptoms. We report the unusual case of a 33‐year‐old Caucasian male with advanced AIDS who presented with upper GI bleeding from diffuse erosions throughout the duodenum.
Michael A. Spinner, Heather N. Paulin, C. William Wester, D. C. Damin, Y. Nakayama, S. Nomura   +5 more
wiley   +1 more source

Drug–drug interactions between gender‐affirming hormone therapy and antiretrovirals for treatment/prevention of HIV

British Journal of Clinical Pharmacology, Volume 90, Issue 10, Page 2366-2382, October 2024.
Transgender persons face a greater burden of HIV compared to cisgender counterparts. Concerns around drug–drug interactions (DDIs) have been cited as reasons for lower engagement in HIV care and lower pre‐exposure prophylaxis (PrEP) uptake among transgender populations.
Tessa Senneker
wiley   +1 more source

Torsade de Pointes due to Methadone Use in a Patient with HIV and Hepatitis C Coinfection

Cardiology Research and Practice, Volume 2010, Issue 1, 2010., 2010
We present a case of Torsade de Pointes secondary to multiple factors including patient susceptibility and iatrogenic influences. Contributing causes are presented, and the approach to treatment is discussed.
Jinu John, Xixi Amley, Gabriel Bombino, Chaim Gitelis, Bernard Topi, Gerald Hollander, Joydeep Ghosh, Brian Olshansky   +7 more
wiley   +1 more source