Cellular immune response induced by dna immunization of mice with drug resistant integrases of hiv-1 clade a offers partial protection against growth and metastatic activity of integrase-expressing adenocarcinoma cells [PDF]
, 2021 Funding Information: Funding: Experiments were supported by the grants of the Russian Science Fund 15-15-30039, Russian Fund for Basic Research 20-04-01034, Latvian Science Fund LZP 2018-2-03-08, and EU-ROPARTNER project “Strengthening and spreading ...
Agapkina, Yulia +20 more
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Audit of Antenatal Testing of Sexually Transmissible Infections and Blood Borne Viruses at Western Australian Hospitals [PDF]
, 2008 In August 2007, the Western Australian Department of Health (DOH) released updated recommendations for testing of sexually transmissible infections (STI) and blood-borne viruses (BBV) in antenates.
Combs, B. G. +3 more
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Divalent metals and pH alter raltegravir disposition in vitro [PDF]
, 2012 Raltegravir shows marked pharmacokinetic variability in patients, with gastrointestinal pH and divalent-metal binding being potential factors. We investigated raltegravir solubility, lipophilicity, pKa, and permeativity in vitro to elucidate known ...
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Potassium: A Vital Regulator of Plant Responses and Tolerance to Abiotic Stresses
, 2018 Among the plant nutrients, potassium (K) is one of the vital elements required for plant growth and physiology. Potassium is not only a constituent of the plant structure but it also has a regulatory function in several biochemical processes related to ...
M. Hasanuzzaman +8 more
semanticscholar +1 more source
Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors [PDF]
, 2010 Background XMRV (xenotropic murine leukemia virus-related virus) is the first known example of an exogenous gammaretrovirus that can infect humans. A limited number of reports suggest that XMRV is intrinsically resistant to many of the antiretroviral ...
A Adachi +65 more
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Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
, 2012 Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
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Adult antiretroviral therapy guidelines 2017 [PDF]
, 2017 These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine in 2014 and the update on when to initiate antiretroviral therapy in 2015.
Carmona, Sergio +15 more
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Patent Pooling for Promoting Access to Antiretroviral Drugs (ARVs) – A Strategic Option for India [PDF]
The current HIV/AIDS scenario in India is quite grim with an estimated 2.4 million people living with HIV/AIDS (PLHA) in 2008, just behind South Africa and Nigeria. The anti-retroviral drugs (ARVs) remain the main stay of global HIV/AIDS treatment.
Boulle A +10 more
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Use and outcomes of contemporary combination antiretroviral therapy in people living with HIV [PDF]
, 2022 The introduction of antiretroviral therapy (ART) has transformed HIV from a fatal illness into a manageable, chronic condition. As there is currently no cure for HIV, ART, typically including three antiretroviral drugs (ARVs), is a lifelong commitment ...
Greenberg, Lauren
core
Synthesis of Ferrocene-Oxadiazole Complexes and a Determination of Their LogD Values [PDF]
, 2016 During the drug design process, there are many different approaches that researchers can take to improve the overall efficacy of a potential drug candidate. Aside from attempting to understand how different functional groups interact with target tissues,
Gould, Grace C.
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