Results 11 to 20 of about 43,574 (244)
Stimulated Raman photoacoustic imaging [PDF]
Proceedings of the National Academy of Sciences, 2010 Achieving label-free, molecular-specific imaging with high spatial resolution in deep tissue is often considered the grand challenge of optical imaging. To accomplish this goal, significant optical scattering in tissues has to be overcome while achieving molecular specificity without resorting to extrinsic labeling.
Vladislav V, Yakovlev +5 more
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Imaging with Raman Spectroscopy [PDF]
Current Pharmaceutical Biotechnology, 2010 Raman spectroscopy, based on the inelastic scattering of a photon, has been widely used as an analytical tool in many research fields. Recently, Raman spectroscopy has also been explored for biomedical applications (e.g. cancer diagnosis) because it can provide detailed information on the chemical composition of cells and tissues.
Yin, Zhang, Hao, Hong, Weibo, Cai
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Raman image-activated cell sorting [PDF]
Nature Communications, 2020 AbstractThe advent of image-activated cell sorting and imaging-based cell picking has advanced our knowledge and exploitation of biological systems in the last decade. Unfortunately, they generally rely on fluorescent labeling for cellular phenotyping, an indirect measure of the molecular landscape in the cell, which has critical limitations.
Nao Nitta +48 more
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Airy light-sheet Raman imaging
Optics Express, 2021 Light-sheet fluorescence microscopy has greatly improved the speed and overall photostability of optically sectioning cellular and multi-cellular specimens. Similar gains have also been conferred by light-sheet Raman imaging; these schemes, however, rely on diffraction limited Gaussian beams that hinder the uniformity and size of the imaging field-of ...
N R, Subedi +6 more
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Imaging with Extrinsic Raman Labels [PDF]
Applied Spectroscopy, 1996 In two separate examples we demonstrate the use of extrinsic Raman scattering probes for imaging of biological samples. First, the distribution of cholesterol in a rat eye lens is determined with the use of the Raman scattered light from filipin, a molecule which binds specifically to cholesterol.
Sijtsema, Nanna M. +4 more
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Raman microspectroscopy fingerprinting of organoid differentiation state
Cellular & Molecular Biology Letters, 2022 Highlights Salivary gland organoids have unique Raman signatures detectable with a confocal-based Raman imaging approach. Raman signatures can be detected in unlabeled fixed or live organoids.
Kate Tubbesing +7 more
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Raman's “Effect” on Molecular Imaging [PDF]
Journal of Nuclear Medicine, 2011 Raman spectroscopy is an optical technique that offers unsurpassed sensitivity and multiplexing capabilities to the field of molecular imaging. In the past, Raman spectroscopy had predominantly been used as an analytic tool for routine chemical analysis, but more recently, researchers have been able to harness its unique properties for imaging and ...
Cristina L, Zavaleta +2 more
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Calibration and testing of a Raman hyperspectral imaging system to reveal powdered food adulteration. [PDF]
PLoS ONE, 2018 The potential adulteration of foodstuffs has led to increasing concern regarding food safety and security, in particular for powdered food products where cheap ground materials or hazardous chemicals can be added to increase the quantity of powder or to ...
Santosh Lohumi +7 more
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PLoS ONE, 2021 The primary plant cell wall is a complex matrix composed of interconnected polysaccharides including cellulose, hemicellulose, and pectin. Changes of this dynamic polysaccharide system play a critical role during plant cell development and ...
Qing He +3 more
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