Results 41 to 50 of about 1,551,165 (345)

Advanced techniques in Raman tweezers microspectroscopy for applications in biomedicine [PDF]

open access: yes, 2008
This thesis investigates the use of Raman tweezers microspectroscopy to interrogate the biochemistry of single biological cells. Raman tweezers microspectroscopy is a powerful technique, which combines traditional Raman microspectroscopy and optical ...
Jess, Phillip R.T.
core   +2 more sources

Raman microscopy of the molybdate minerals koechlinite, iriginite and lindgrenite [PDF]

open access: yes, 2004
A series of molybdate bearing minerals including wulfenite, powellite, lindgrenite and iriginite have been analysed by Raman microscopy. These minerals are closely related and often have related paragenesis.
Weier, Matt L.   +2 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Accumulation of Spherical Microplastics in Earthworms Tissues-Mapping Using Raman Microscopy

open access: yesApplied Sciences
The presence of microplastics in the environment is now becoming a challenge for many scientific disciplines. Molecular diversity and spatial migration make it difficult to find plastic-free areas.
Marek Klimasz, Anna Grobelak
doaj   +1 more source

Correlative Fluorescence and Raman Microscopy to Define Mitotic Stages at the Single-Cell Level: Opportunities and Limitations in the AI Era

open access: yesBiosensors, 2023
Nowadays, morphology and molecular analyses at the single-cell level have a fundamental role in understanding biology better. These methods are utilized for cell phenotyping and in-depth studies of cellular processes, such as mitosis.
Csaba Voros   +11 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Stimulated Raman Scattering Microscopy: A Review

open access: yesPhotonics
Stimulated Raman scattering (SRS) microscopy is a high-speed imaging modality based on intrinsic molecular vibrations, producing chemical maps in living systems.
Rajeev Ranjan, Luigi Sirleto
doaj   +1 more source

Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis [PDF]

open access: yes, 2012
The work was funded by CR-UK/EPSRC/MRC/DoH (England) imaging programme.In the field of biomedical optics, Raman spectroscopy is a powerful tool for probing the chemical composition of biological samples.
Ashok, Praveen Cheriyan   +9 more
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Imaging Drug Uptake by Bioorthogonal Stimulated Raman Scattering Microscopy

open access: yes, 2017
Stimulated Raman scattering (SRS) microscopy in tandem with bioorthogonal Raman labelling strategies is set to revolutionise the direct visualisation of intracellular drug uptake.
Lee, Martin   +4 more
core   +1 more source

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