This study aimed to develop xerogels for delivery of aspirin via the oral (buccal mucosa and GIT) route in geriatric patients with dysphagia. Xerogels were prepared using low molecular weight chitosan (CS), carrageenan (CAR) and metolose (MET) in ...
Smirna Farias
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Stimulated Raman scattering microscopy on biological cellular machinery
Benefiting from the developments of advanced optical microscopy techniques, the mysteries of biological functions at the cellular and subcellular levels have been continuously revealed.
Jing Huang, Minbiao Ji
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Correlative force and tip-enhanced Raman microscopy
Tip-enhanced Raman scattering (TERS) microscopy attracts increasing attention for visualization and characterization of strain distribution on crystalline samples at a nanoscale due to nano-sized fields localized at a metal tip. However, as the metal tip
Kohta Saitoh +2 more
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Advanced techniques in Raman tweezers microspectroscopy for applications in biomedicine [PDF]
This thesis investigates the use of Raman tweezers microspectroscopy to interrogate the biochemistry of single biological cells. Raman tweezers microspectroscopy is a powerful technique, which combines traditional Raman microspectroscopy and optical ...
Jess, Phillip R.T.
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Coherent Raman Scattering Microscopy in Oncology Pharmacokinetic Research
The high attrition rates of anti-cancer drugs during clinical development remains a bottleneck problem in pharmaceutical industry. This is partially due to the lack of quantitative, selective, and rapid readouts of anti-cancer drug activity in situ with ...
Junjie Zeng +3 more
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Optimisation of wavelength modulated Raman spectroscopy : towards high throughput cell screening [PDF]
In the field of biomedicine, Raman spectroscopy is a powerful technique to discriminate between normal and cancerous cells. However the strong background signal from the sample and the instrumentation affects the efficiency of this discrimination ...
Andrew Riches +17 more
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Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis [PDF]
The work was funded by CR-UK/EPSRC/MRC/DoH (England) imaging programme.In the field of biomedical optics, Raman spectroscopy is a powerful tool for probing the chemical composition of biological samples.
Ashok, Praveen Cheriyan +9 more
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Visualization of Epidermal Reservoir Formation from Topical Diclofenac Gels by Raman Spectroscopy
Qihong Zhang,1 Carol R Flach,1 Richard Mendelsohn,1 Leanne Page,2 Susan Whitson,2 Mila Boncheva Bettex3 1Department of Chemistry, Rutgers University, Newark, NJ 07102, USA; 2Charles River Laboratories Edinburgh Ltd., Tranent, East Lothian, UK; 3GSK ...
Zhang Q +5 more
doaj
Automated particle analysis by Raman microscopy – a method development
Chemical identification of particles increasingly gains importance concerning regulatory affairs of medical devices. Particle numbers of samples very easily add up to orders larger than 1.000.
Reske Thomas +5 more
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In-situ observation and atomic resolution imaging of the ion irradiation induced amorphisation of graphene [PDF]
Ion irradiation has been observed to induce a macroscopic flattening and in-plane shrinkage of graphene sheets without a complete loss of crystallinity.
Greaves, Graeme +10 more
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