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Quantifying Cellular Nanoplastic Accumulation Using Raman Microscopy [PDF]

ACS Omega
Federico Perrella, Valentina Iezzi, Roberta Maria Ferri, Giulia Fioravanti, Marilena Briglia, Andrea Marini, Elisabetta Benedetti, Paola Benassi, Carino Ferrante, Davide Tedeschi   +9 more
doaj   +3 more sources

Bessel-beam illumination Raman microscopy. [PDF]

Biomed Opt Express, 2022
We demonstrate the use of Bessel beams for side illumination slit-scanning Raman imaging for label-free and hyperspectral analysis of cell spheroids. The background elimination by the side illumination and the aberration-resistant Bessel beam drastically improves the image contrast in Raman observation, allowing label-free investigation of ...
Bando K, Yabuuchi S, Li M, Kubo T, Oketani R, Smith NI, Fujita K.   +6 more
europepmc   +3 more sources

Confocal Raman Microscopy with Adaptive Optics. [PDF]

ACS Photonics
Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further reduce these signals, requiring even longer acquisition times.
Muñoz-Bolaños JD, Rajaeipour P, Kummer K, Kress M, Ataman ÇL, Ritsch-Marte M, Jesacher A.   +6 more
europepmc   +4 more sources

Non-Uniform Distribution of Cryoprotecting Agents in Rice Culture Cells Measured by CARS Microscopy

Plants, 2021
Cryoprotectants allow cells to be frozen in liquid nitrogen and cryopreserved for years by minimizing the damage that occurs in cooling and warming processes.
Fionna M. D. Samuels, Dominik G. Stich, Remi Bonnart, Gayle M. Volk, Nancy E. Levinger   +4 more
doaj   +1 more source

Assessment of Prediction Models for Punch Sticking in Tablet Formulations

British Journal of Pharmacy, 2022
Punch sticking is a common tablet compression manufacturing issue experienced during late-stage large-scale manufacturing. Prediction of punch sticking propensity and identification of the sticking component is important for early-stage formulation ...
Edward Paul Rhodes, Jeremy Everett , Paul Whiteside, Debbie Kraus, Michael Cram, Neil Dawson   +5 more
doaj   +1 more source

Formation mechanisms of sub-micron pharmaceutical composite particles derived from far- and near-field Raman microscopy

Journal of Pharmaceutical Analysis, 2021
Surface enhanced Raman spectroscopy (SERS) and confocal Raman microscopy are applied to investigate the structure and the molecular arrangement of sub-micron furosemide and polyvinylpyrrolidone (furosemide/PVP) particles produced by spray flash ...
Jakob Hübner, Jean-Baptiste Coty, Yan Busby, Denis Spitzer   +3 more
doaj   +1 more source

Applicability of Confocal Raman Microscopy to Observe Microstructural Modifications of Cream Cheeses as Influenced by Freezing

Foods, 2020
Confocal Raman microscopy is a promising technique to derive information about microstructure, with minimal sample disruption. Raman emission bands are highly specific to molecular structure and with Raman spectroscopy it is thus possible to observe ...
Marcello Alinovi, Germano Mucchetti, Ulf Andersen, Tijs A. M. Rovers, Betina Mikkelsen, Lars Wiking, Milena Corredig   +6 more
doaj   +1 more source

The combination of Raman microscopy and electron microscopy – Practical considerations of the influence of vacuum on Raman microscopy

Micron, 2021
Due to the specific vacuum requirements for scanning electron microscopy (SEM), the Raman microscope has to operate in vacuum in a correlative Raman-SEM, which is a type of microscope combination that has recently increased in popularity. This works considers the implications of conducting Raman microscopy under vacuum, as opposed to operating in ...
Harald Fitzek, Karin Wewerka, Ute Schmidt, Hartmuth Schröttner, Armin Zankel   +4 more
openaire   +2 more sources

Coherent Stokes Raman scattering microscopy (CSRS)

Nature Communications, 2023
We report the first implementation of laser scanning coherent Stokes Raman scattering (CSRS) microscopy. To overcome the major challenge in CSRS imaging, we show how to suppress the fluorescence background by narrow bandpass filter and a lock-in based ...
Sandro Heuke, Hervé Rigneault
doaj   +1 more source

Raman Microscopy: Complement or Competitor? [PDF]

, 2010
The objective of this chapter is to provide an introduction to Raman spectroscopic microscopy and its potential for biochemical analysis and clinical diagnostic applications, such that it can be compared and contrasted to the techniques of synchrotron and bench-top mid-FTIR spectroscopy discussed el...
Byrne, Hugh, Sockalingum, Ganesh, Stone, Nick   +2 more
openaire   +2 more sources