Results 171 to 180 of about 30,184 (259)
Advanced Science, EarlyView.xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben +4 more
wiley +1 more source
A Fast Slicing Method for Colored Models Based on Colored Triangular Prism and OpenGL. [PDF]
Micromachines (Basel)Xia L, Yan R.
europepmc +1 more source
Advanced Science, EarlyView.This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang +12 more
wiley +1 more source
5G Network Slicing: Security Challenges, Attack Vectors, and Mitigation Approaches. [PDF]
Sensors (Basel)Dias J, Pinto P, Santos R, Malta S.
europepmc +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Advanced Science, EarlyView.Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
Optimizing data transmission in 6G software defined networks using deep reinforcement learning for next generation of virtual environments. [PDF]
Sci RepNaguib KM +3 more
europepmc +1 more source
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
The Interplay Among Biomolecules and Nanomaterials. [PDF]
Int J Mol SciJia R.
europepmc +1 more source
Heuristically Adaptive Diffusion‐Model Evolutionary Strategy
Advanced Science, EarlyView.Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl +3 more
wiley +1 more source
A Comprehensive Overview of Network Slicing for Improving the Energy Efficiency of Fifth-Generation Networks. [PDF]
Sensors (Basel)Lorincz J, Kukuruzović A, Blažević Z.
europepmc +1 more source