Functional microRNA targeting without seed pairing. [PDF]
Hall MH, Wang PY, Pham TM, Bartel DP.
europepmc +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Slice-aware 5G network orchestration framework based on dual-slice isolation and management strategy (D-SIMS). [PDF]
Venkatapathy S +5 more
europepmc +1 more source
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
Can paleontologists pinpoint the dawn of the dinosaurs? [PDF]
McDermott A.
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Moxibustion alleviates autophagy and inhibits ferroptosis to improve cardiac function in rats with post-myocardial infarction heart failure. [PDF]
Bing G +9 more
europepmc +1 more source
A Survey on Green Enablers: A Study on the Energy Efficiency of AI-Based 5G Networks. [PDF]
Ezzeddine Z +3 more
europepmc +1 more source
On the Security of Cell-Free Massive MIMO Networks. [PDF]
Mohammed H +4 more
europepmc +1 more source
Adipose-Specific GHR Deletion Attenuates Brain Aging and Cognitive Decline in Aged Mice. [PDF]
Zhang Y +6 more
europepmc +1 more source

