Retinoic acid treatment recruits macrophages and increases axonal regeneration after optic nerve injury in the frog Rana pipiens [PDF]
Retinoic acid (RA) plays major roles during nervous system development, and during regeneration of the adult nervous system. We have previously shown that components of the RA signaling pathway are upregulated after optic nerve injury, and that exogenous
Valeria De La Rosa-Reyes +3 more
doaj +3 more sources
Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and Its Truncated Analogues [PDF]
Antimicrobial peptides (AMPs) are considered as a promising agent to overcome the drug-resistance of bacteria. Large numbers of AMPs have been identified from the skin secretion of Rana pipiens, including brevinins, ranatuerins, temporins and esculentins.
Xiaowei Zhou +9 more
doaj +2 more sources
Landscape genetics reveal broad and fine‐scale population structure due to landscape features and climate history in the northern leopard frog (Rana pipiens) in North Dakota [PDF]
Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current
Justin M. Waraniak +4 more
doaj +2 more sources
Application of CNTF or FGF-2 increases the number of M2-like macrophages after optic nerve injury in adult Rana pipiens. [PDF]
We have previously shown that a single application of the growth factors ciliary neurotrophic factor (CNTF) or fibroblast growth factor 2 (FGF-2) to the crushed optic nerve of the frog, Rana pipiens, increases the numbers and elongation rate of ...
Rosa E Blanco +4 more
doaj +2 more sources
Prevalence of the pathogenic chytrid fungus,
Background Emerging infectious diseases threaten naïve host populations with extinction. Chytridiomycosis, an emerging infectious disease of amphibians, is caused by the pathogenic fungus Batrachochytrium dendrobatidis (Bd) and has been linked to global ...
Govindarajulu Purnima +4 more
doaj +2 more sources
Discovery, development and optimisation of a novel frog antimicrobial peptide with combined mode of action against drug-resistant bacteria [PDF]
Antimicrobial peptides (AMP) have emerged as promising candidates for addressing the clinical challenges posed by the rapid evolution of antibiotic-resistant microorganisms.
Jingkai Wang +10 more
doaj +2 more sources
Outbreak of parasite-induced limb malformations in a declining amphibian species in Colorado [PDF]
The detection of severe limb malformations in metamorphosing northern leopard frogs (Rana pipiens) from a Colorado pond in August 2022 prompted questions about the cause(s) and concern over the implications.
Pieter T.J. Johnson +5 more
doaj +2 more sources
Follow-up ecological studies for cryptic species discoveries: Decrypting the leopard frogs of the eastern U.S. [PDF]
Cryptic species are a challenge for systematics, but their elucidation also may leave critical information gaps about the distribution, conservation status, and behavior of affected species. We use the leopard frogs of the eastern U.S. as a case study of
Matthew D Schlesinger +18 more
doaj +1 more source
In vivo muscle force and muscle power during near-maximal frog jumps. [PDF]
Frogs' outstanding jumping ability has been associated with a high power output from the leg extensor muscles. Two main theories have emerged to explain the high power output of the frog leg extensor muscles, either (i) the contractile conditions of all ...
Eng Kuan Moo +4 more
doaj +1 more source
Localized carry‐over effects of pond drying on survival, growth, and pathogen defenses in amphibians
Climate change is increasing variability in precipitation patterns in many parts of the globe. Unpredictable changes in water availability can be particularly challenging for organisms that rely on precipitation‐fed water sources for completing their ...
Emily H. Le Sage +16 more
doaj +1 more source

