Results 101 to 110 of about 3,189,503 (269)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
SOME SYSTEMATIC SAMPLING STRATEGIES USING MULTIPLE RANDOM STARTS
Pakistan Journal of Statistics and Operation Research, 2010 In this paper an attempt is made to extend linear systematic sampling using multiple random starts due to Gautschi(1957)for various types of systematic sampling schemes available in literature, namely(i) Balanced Systematic Sampling (BSS) of Sethi (1965) and (ii) Modified Systematic Sampling (MSS) of Singh, Jindal, and Garg (1968).
Sampath Sundaram, Ammani Sivaraman
openaire +2 more sources
TechnologiesIn order to achieve fast and accurate life damage online monitoring of the steam turbine rotor, it was significant to propose an empirical-statistical model using a machine learning algorithm instead of finite element simulation to improve the effect of ...
Wenhe Liu +8 more
doaj +1 more source
Genetics and Molecular Biology, 2007 Heritabilities and genetic correlations in a Canchim beef cattle herd were estimated using data on the following traits: male scrotal circumference at twelve months (SC12); days to first calving (DFC) for heifers; days to calving (DC) for cows; male and ...
Talita Buttarello Mucari +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PLoS Neglected Tropical DiseasesThe Pacific Island Countries and territories (PICs) experienced a doubling of annual reported dengue outbreaks between 2012 to 2019, including concurrent outbreaks of multiple dengue serotypes.
Justin Sexton +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source