Results 91 to 100 of about 319,639 (338)

Quantization from Hamilton-Jacobi theory with a random constraint

, 2012
We propose a method of quantization based on Hamilton-Jacobi theory in the presence of a random constraint due to the fluctuations of a set of hidden random variables.
Agung Budiyono, Aharonov, Ali, Allahverdyan, Bohm, Bohm, Bohm, Budiyono, Budiyono, Calogero, Gaveau, Holland, Nelson, Nelson, Philippidis, Philippidis, Rund, Rund, Wiseman   +18 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Random attractors in $H^1$ for stochastic two dimensional micropolar fluid flows with spatial-valued noises

Electronic Journal of Differential Equations, 2014
This work studies the long-time behavior of two-dimensional micropolar fluid flows perturbed by the generalized time derivative of the infinite dimensional Wiener processes.
Wenqiang Zhao
doaj  

Compiling Probabilistic, Bio-Inspired Circuits on a Field Programmable Analog Array

Frontiers in Neuroscience, 2014
A field programmable analog array (FPAA) is presented as an energy efficiency engine: a mixed mode processor for which functions can be compiled at significantly less energy costs using noisy computing circuits.
H. Bo eMarr, Jennifer eHasler
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Topological dimensions of random attractors for a stochastic reaction-diffusion equation with delay

Electronic Journal of Qualitative Theory of Differential Equations
The aim of this paper is to obtain an estimation of Hausdorff as well as fractal dimensions of random attractors for a stochastic reaction-diffusion equation with delay.
Wenjie Hu, Tomas Caraballo
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Mean-square random dynamical systems

Journal of Differential Equations, 2012
Two-parameter semigroups operating on the space \(L^2(\Omega,P;\mathbb R^d)\) of square-integrable \(\mathbb R^d\)-valued random variables are introduced in order to investigate random or stochastic differential equations with non-local coefficients. Assuming exponential contraction of differences of trajectories in the course of time, uniform in the ...
Kloeden, Peter E., Lorenz, Thomas
openaire   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source