Results 71 to 80 of about 40,691 (307)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
On Koopman and Perron-Frobenius operators of random dynamical systems
ESAIM: Proceedings and Surveys, 2014 In this paper, we investigate the Koopman and the Perron-Frobenius operators of random dynamical systems in general setting. Moreover, we give some necessary and sufficient conditions for the existence of invariant densities for the ...
Hmissi Mohamed
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Central Limit Theorem for Random Dynamical Systems [PDF]
, 2016 We consider random dynamical systems with randomly chosen jumps. The choice of deterministic dynamical system and jumps depends on a position.
Horbacz, Katarzyna, Katarzyna Horbacz
core +1 more source
Random Attractors for the Stochastic Discrete Long Wave-Short Wave Resonance Equations
Journal of Applied Mathematics, 2011 We prove the existence of the random attractor for the stochastic discrete long wave-short wave resonance equations in an infinite lattice. We prove the asymptotic compactness of the random dynamical system and obtain the random attractor.
Jie Xin, Hong Lu
doaj +1 more source
Compiling Probabilistic, Bio-Inspired Circuits on a Field Programmable Analog Array
Frontiers in Neuroscience, 2014 A field programmable analog array (FPAA) is presented as an energy efficiency engine: a mixed mode processor for which functions can be compiled at significantly less energy costs using noisy computing circuits.
H. Bo eMarr, Jennifer eHasler
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source