Results 121 to 130 of about 40,691 (307)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Random uniform exponential attractor for stochastic non-autonomous reaction-diffusion equation with multiplicative noise in ℝ3

open access: yesOpen Mathematics, 2019
We first introduce the concept of the random uniform exponential attractor for a jointly continuous non-autonomous random dynamical system (NRDS) and give a theorem on the existence of the random uniform exponential attractor for a jointly continuous ...
Han Zongfei, Zhou Shengfan
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The narrow recurrence of random dynamical systems

open access: yesMathematica Bohemica
Summary: Let \((\Omega ,\mathcal{F},\mathbb{P})\) be a probability space, where \(\mathcal{F}\) is countably generated, and \(X\) be a Polish space. Let \(\varphi\) be a random dynamical system with time \(\mathbb{T}\) on \(X\). The skew product flow \(\{\Theta_{t},\ t\in\mathbb{T}\}\) induced by \(\varphi\) is a family of continuous operators acting ...
Ahmed Zaou, Mohamed Amouch
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

A Note on Covariance Stationarity Conditions for Dynamic Random Coefficient Models [PDF]

open access: yes
In this note we look at sufficient conditions for stationarity of a simple random coefficient model and find that this model is guaranteed to be stationary under strict conditions. J.E.L.
George Kapetanios
core  

Simple Rules of a Discrete Stochastic Process Leading to Catalan-like Recurrences

open access: yesAlgorithms
A method for obtaining integer sequences is presented by defining simple rules for the evolution of a discrete dynamical system. This paper demonstrates that various Catalan-like recurrences of known integer sequences can be obtained from a single ...
Mariusz Białecki
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

A coupled parametric and nonparametric approach for modal analysis of a satellite [PDF]

open access: yes, 2013
This study takes place in the context of dynamical prediction for satellite structures. Aims of such studies are to survey the dynamical response of satellite equipment and components, to check that requirements are correct and to give prediction of ...
Salaün, Michel   +2 more
core  

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