Results 71 to 80 of about 306,029 (281)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Upper semicontinuity of random attractors for non-compact random dynamical systems

Electronic Journal of Differential Equations, 2009
The upper semicontinuity of random attractors for non-compact random dynamical systems is proved when the union of all perturbed random attractors is precompact with probability one.
Bixiang Wang
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Learning dynamical systems with hit-and-run random feature maps

Nature Communications
We show how random feature maps can be used to forecast dynamical systems with excellent forecasting skill. We consider the tanh activation function and judiciously choose the internal weights in a data-driven manner such that the resulting features ...
Pinak Mandal, Georg A. Gottwald
doaj   +1 more source

Center manifolds for random dynamical systems with generalized trichotomies

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, we consider small perturbations of linear Random Dynamical Systems evolving on a Banach space and admitting a general form of trichotomy.
António Bento, Helder Vilarinho
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Quasi-random dynamical systems [PDF]

Mathematical Notes of the Academy of Sciences of the USSR, 1969
This paper is the author's abstract of his dissertation for the degree Doctor of Physiomathematical Science. The dissertation was defended on March 7, 1969, in the Study of the Soviet Mechanical-Mathematical Faculty of the M. V. Lomonosov Moscow State University. Official opponents: Academician A. N. Kolmogorov, Dr. of Physicomathematical Sciences D. V.
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Random Attractors for Stochastic Retarded Reaction-Diffusion Equations on Unbounded Domains

Abstract and Applied Analysis, 2013
This paper is devoted to a stochastic retarded reaction-diffusion equation on all d-dimensional space with additive white noise. We first show that the stochastic retarded reaction-diffusion equation generates a random dynamical system by transforming ...
Xiaoquan Ding, Jifa Jiang
doaj   +1 more source

Random attractors for stochastic two-compartment Gray-Scott equations with a multiplicative noise

Open Mathematics, 2016
In this paper, we consider the existence of a pullback attractor for the random dynamical system generated by stochastic two-compartment Gray-Scott equation for a multiplicative noise with the homogeneous Neumann boundary condition on a bounded domain of
Jia Xiaoyao, Gao Juanjuan, Ding Xiaoquan
doaj   +1 more source