Results 131 to 140 of about 1,238,639 (328)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Comparative Analysis of Machine Learning Methods in Predicting Diabetes Risk Based on Genetic Data

open access: yesJISA (Jurnal Informatika dan Sains)
Type 2 Diabetes Mellitus (T2DM) is a global chronic disease caused by the interaction of genetic and environmental factors. The use of genetic data offers great potential for early detection and personalized intervention. However, the complex analysis of
Sekar Ayu Wijaya Kusumaningrum   +2 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Chronology of the development of active queue management algorithms of RED family. Part 3: from 2016 up to 2024

open access: yesDiscrete and Continuous Models and Applied Computational Science
This work is the first part of a large bibliographic review of active queue management algorithms of the Random Early Detection (RED) family, presented in the scientific press from 1993 to 2023.
Ivan S. Zaryadov   +3 more
doaj   +1 more source

Survey on Random Early Detection Mechanism and Its Variants

open access: yesIOSR Journal of Computer Engineering, 2012
Active Queue Management (AQM) algorithms are an Implementing schemes, So that packets are transmitted with higher priority than others. Random Early Detection (RED) is the first active queue management algorithm proposed for deployment in TCP/IP networks.
openaire   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Early Detection Initiative: A randomized controlled trial of algorithm-based screening in patients with new onset hyperglycemia and diabetes for early detection of pancreatic ductal adenocarcinoma

open access: hybrid, 2021
Suresh T. Chari   +11 more
openalex   +1 more source

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