The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Detection and Classification of Kidney Disease from CT Images: An Automated Deep Learning Approach
Kidney disease is a social and global health concern where early detection is crucial to reducing mortality and improving treatment outcomes. Traditional diagnostic methods are time-consuming and prone to human error.
Md Nazir Hossain +5 more
doaj +1 more source
Controlling Delay at the Router Buffer using Modified Random Early Detection
Active Queue Management (AQM) methods are used to manage the buffer of the network routers and avoid the problems caused by network congestion, especially packet loss. Among various AQM methods that have been proposed in the literature, Random Early Detection (RED)method has proved to stabilize the network performance under various traffic loads ...
openaire +1 more source
Review of random early detection optimization for congestion control in vehicular ad hoc networks
Muayad Mubarak Mohamed Ali +4 more
openalex +2 more sources
Integrated Random Early Detection for Congestion Control at the Router Buffer [PDF]
Ahmad Adel Abu-Shareha
openalex +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
Improved random early detection congestion control algorithm for internet routers
Samuel O. Hassan +5 more
openalex +2 more sources
Early Detection of Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial [PDF]
Anthony Chapron +2 more
openalex +1 more source

