Results 81 to 90 of about 1,238,639 (328)

Anomaly Detection Based on Indicators Aggregation

, 2014
Automatic anomaly detection is a major issue in various areas. Beyond mere detection, the identification of the source of the problem that produced the anomaly is also essential.
Cottrell, Marie, Lacaille, Jérôme, Rabenoro, Tsirizo, Rossi, Fabrice   +3 more
core   +3 more sources

Segmentation based early Melanoma Detection Using Random Forest Algorithm

, 2023
Abstract This article proposes a method to detect melanoma at the early stage before it becomes something severe. The lesion of melanoma has five stages, stage zero to stage four, of which stage one and stage two are early stages. Melanoma is mainly caused by UV radiation, unhealthy lifestyle, hereditary etc.; In addition, age and gender (sex ...
Mesfin Abate, Jemal Hussein, V. K. Varadarajan, Solomon Zemene   +3 more
openaire   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Implementation of the Random Forest Algorithm with Optuna Optimization in Lung Cancer Classification

Sistemasi: Jurnal Sistem Informasi
Lung cancer remains one of the leading causes of death worldwide, with many sufferers unaware of their condition until it is too late for treatment. Therefore, high-accuracy prediction methods are urgently needed for early detection of lung cancer.
Ahmad Ainul Yaqin, Mula Agung Barata, Nur Mahmudah   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Advanced interpretable diagnosis of Alzheimer's disease using SECNN-RF framework with explainable AI

Frontiers in Artificial Intelligence
Early detection of Alzheimer's disease (AD) is vital for effective treatment, as interventions are most successful in the disease's early stages. Combining Magnetic Resonance Imaging (MRI) with artificial intelligence (AI) offers significant potential ...
Nabil M. AbdelAziz, Wael Said, Mohamed M. AbdelHafeez, Asmaa H. Ali   +3 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

ANALISIS DETERMINAN TERLAMBATNYA DETEKSI DINI PENDERITA KUSTA DI KECAMATAN JENGGAWAH JEMBER 2008 (Determinan Analysis Late Early Detections Of Leprosy's Patient At Jenggawah) Jember 2008) [PDF]

, 2008
Leprosy is infectious disease which causes disability that can be prevented by early detection and also regularity treatment and care. Proportion of disability grade 2 at Jenggawah subdistric is 38,3% at 2008.
Ayu Palupi, Widya, Prasetyowati, Irma, Ramani, Andrei   +2 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source