Results 91 to 100 of about 4,395,518 (296)
Housing Demand with Random Group Effects [PDF]
This paper examines the random group effect, which has usually not been considered in traditional housing demand studies. Frequently, group level variables are used in housing demand estimation due to the data constraint.
Sue-Jing Lin, Wen-chieh Wu
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Bayesian views of generalized additive modelling
Generalized additive models (GAMs) are a frequently used, flexible framework applied to many problems in statistical ecology. They are commonly used to incorporate smooth effects into models via splines, including spatial components in species ...
David L. Miller
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Random effects in drug dissolution
The deterministic models of dissolution are commonly used in pharmaceutical studies, however, experimental results point to stochastic nature of the dissolution processes. In this paper we present stochastic modifications of deterministic models using the concept of Wiener process.
Jakub, Cupera, Petr, Lansky
openaire +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Influence of Market Power and Market Trends on Grid Market Signals
This article investigates the premium and discount incentive mechanisms in the fed cattle grid pricing system. A pooled cross-sectional dataset containing carcass information on 598 fed steers evaluated weekly on the AMS publicly reported price grid was ...
Scott Fausti +3 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Uncertainty under a multivariate nested-error regression model with logarithmic transformation [PDF]
Assuming a multivariate linear regression model with one random factor, we consider the parameters defined as exponentials of mixed effects, i.e., linear combinations of fixed and random effects.
Molina, Isabel
core +1 more source

