Results 51 to 60 of about 1,535,509 (313)

Linear Mixed Models: Gum and Beyond

Measurement Science Review, 2014
In Annex H.5, the Guide to the Evaluation of Uncertainty in Measurement (GUM) [1] recognizes the necessity to analyze certain types of experiments by applying random effects ANOVA models.
Arendacká Barbora, Täubner Angelika, Eichstädt Sascha, Bruns Thomas, Elster Clemens   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Applying Linear Mixed Effects Models with Crossed Random Effects to Psycholinguistic Data: Multilevel Specification and Model Selection. [PDF]

Tutorials in Quantitative Methods for Psychology, 2015
Applying linear mixed effects regression (LMER) models to psycholinguistic data was made popular by Baayen, Davidson, and Bates (2008). However, applied researchers sometimes encounter model specification difficulties when using such models.
Hsiu-Ting Yu
doaj   +2 more sources

Multilevel Intersectional Analysis to Identify Extreme Profiles in Italian Student Achievement Data

Social Sciences
Students have diverse identities and social characteristics. The different combinations of these factors create a stratification that affects the learning outcomes.
Enrico Contin, Leonardo Grilli
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Effects of drinking water, sanitation, handwashing, and nutritional interventions on immune status in young children: a cluster-randomized controlled trial in rural Bangladesh [PDF]

, 2021
Audrie Lin, Andrew Mertens, Sophia T. Tan, Md Ziaur Rahman, Lisa Hester, Lisa E. Kim, Benjamin F. Arnold, Md. Rabiul Karim, Sunny Shahriar, Shahjahan Ali, Abul K Shoab, Md Saheen Hossen, Palash Mutsuddi, Syeda L Famida, Salma Akther, Mahbubur Rahman, Leanne Unicomb, Zachary Butzin-Dozier, Caitlin Hemlock, Alan Hubbard, Christine P. Stewart, Lia C. H. Fernald, John M. Colford, Stephen P. Luby, Firdaus S. Dhabhar   +24 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data Using MCMC

Journal of Statistical Software, 2016
Joint models for longitudinal and time-to-event data constitute an attractive modeling framework that has received a lot of interest in the recent years.
Dimitris Rizopoulos
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Empirical Bayes for group (DCM) studies: a reproducibility study

Frontiers in Human Neuroscience, 2015
This technical note addresses some key reproducibility issues in the dynamic causal modelling of group studies of event related potentials. Specifically, we address the reproducibility of Bayesian model comparison (and inferences about model parameters ...
Vladimir eLitvak, Marta eGarrido, Peter eZeidman, Karl eFriston   +3 more
doaj   +1 more source