Results 41 to 50 of about 3,644,468 (346)

Incorporating random effects in biopharmaceutical control strategies

AAPS Open, 2023
Objective Random effects are often neglected when defining the control strategy for a biopharmaceutical process. In this article, we present a case study that highlights the importance of considering the variance introduced by random effects in the ...
Thomas Oberleitner, Thomas Zahel, Marco Kunzelmann, Judith Thoma, Christoph Herwig   +4 more
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Outlier identification and monitoring of institutional or clinician performance: an overview of statistical methods and application to national audit data

BMC Health Services Research, 2023
Background Institutions or clinicians (units) are often compared according to a performance indicator such as in-hospital mortality. Several approaches have been proposed for the detection of outlying units, whose performance deviates from the overall ...
Menelaos Pavlou, Gareth Ambler, Rumana Z. Omar, Andrew T. Goodwin, Uday Trivedi, Peter Ludman, Mark de Belder   +6 more
doaj   +1 more source

Power formulas for mixed effects models with random slope and intercept comparing rate of change across groups [PDF]

, 2021
Yu Zhao, Steven D. Edland
openalex   +1 more source

Damage spreading in random field systems

, 1997
We investigate how a quenched random field influences the damage spreading transition in kinetic Ising models. To this end we generalize a recent master equation approach and derive an effective field theory for damage spreading in random field systems ...
Campbell I A, Coniglio A, Costa U, Derrida B, Derrida B, Glotzer S C, Grassberger P, Hinrichsen H, Kauffman A, Le Caër G, Schuster H G, Tamarit F A, Thomas Vojta, Vojta T, Vojta T, Wang F, Wang F   +16 more
core   +1 more source

TMB: Automatic Differentiation and Laplace Approximation [PDF]

, 2015
TMB is an open source R package that enables quick implementation of complex nonlinear random effect (latent variable) models in a manner similar to the established AD Model Builder package (ADMB, admb-project.org).
Bell, Brad, Berg, Casper W., Kristensen, Kasper, Nielsen, Anders, Skaug, Hans   +4 more
core   +4 more sources

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Pseudo Bayesian Estimation of One-way ANOVA Model in Complex Surveys

, 2020
We devise survey-weighted pseudo posterior distribution estimators under 2-stage informative sampling of both primary clusters and secondary nested units for a one-way ANOVA population generating model as a simple canonical case where population model ...
Savitsky, Terrance D., Williams, Matthew R.   +1 more
core  

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

A Comparison of Methods for Specifying Optimal Random Effects Structures

Methodology, 2023
Using Monte Carlo simulations, this study compared the performance of various approaches to the specification of random effects structures in linear mixed effects models (LMMs), including the minimal approach, the maximal approach, the forward search ...
Wen Luo, Haoran Li
doaj   +1 more source