Results 51 to 60 of about 1,762,172 (296)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Heavy tailed solutions of multivariate smoothing transforms
, 2013 Let $N > 1$ be a fixed integer and $(C_1,..., C_N,Q)$ a random element of $GL(d, \R)^N x \R^d$. We consider solutions of multivariate smoothing transforms, i.e.
Alsmeyer +33 more
core +1 more source
On H(D)-valued random elements
Lietuvos matematikos rinkinys, 2001 There is not abstract.
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AgronomyCarbon (C), nitrogen (N), and phosphorus (P) act as pivotal regulators of biogeochemical cycles, steering organic matter decomposition and carbon sequestration in terrestrial ecosystems through the stoichiometric properties of photosynthetic organs ...
Mingxue Xiang +6 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Xibei Gongye Daxue Xuebao, 2019 The representative volume element(RVE) of the computational micromechanics is established with random fiber distribution being generated by random sequential expansion algorithm.
doaj +1 more source
The Power of Choice in Priority Scheduling
, 2017 Consider the following random process: we are given $n$ queues, into which elements of increasing labels are inserted uniformly at random. To remove an element, we pick two queues at random, and remove the element of lower label (higher priority) among ...
Alistarh, Dan +3 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source