Results 151 to 160 of about 5,590 (258)

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li   +13 more
wiley   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

open access: yesAdvanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou   +10 more
wiley   +1 more source

Programmable Multi‐Axially Aligned Aerogels via Sequential Freeze‐Casting for Tailored Anisotropy and Tunable Mechanics

open access: yesAdvanced Science, EarlyView.
Conventional single‐gradient freeze‐casting typically produces unidirectional porous architectures with limited transverse connectivity. The Sequential Hybridization by Infiltration and Freeze‐casting Technique (SHIFT) addresses this constraint by integrating secondary aligned structures within a preformed primary scaffold.
Kiho Sung, Sungchul Shin
wiley   +1 more source

Thulium Fiber Laser Versus Holmium Laser for Ureteroscopic Lithotripsy: A Systematic Review and Meta-Analysis. [PDF]

open access: yesMedicina (Kaunas)
Ahn HK   +7 more
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang   +8 more
wiley   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

open access: yesAdvanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar   +4 more
wiley   +1 more source

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