Results 51 to 60 of about 1,718,862 (286)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Screening of charged singularities of random fields [PDF]

open access: yes, 2004
Many types of point singularity have a topological index, or 'charge', associated with them. For example the phase of a complex field depending on two variables can either increase or decrease on making a clockwise circuit around a simple zero, enabling ...
Berry M V   +8 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Determining of the Joint Roughness Coefficient (JRC) of Rock Discontinuities Based on the Theory of Random Fields

open access: yesGeosciences, 2019
This work intends to embed the estimation of the joint roughness coefficient (JRC) in the framework of random fields. The random field method is a probabilistic approach which involves modeling of the spatial variability of the pertinent physical ...
Elias Gravanis, Lysandros Pantelidis
doaj   +1 more source

Infinite divisibility of random fields admitting an integral representation with an infinitely divisible integrator

open access: yes, 2009
We consider random fields that can be represented as integrals of deterministic functions with respect to infinitely divisible random measures and show that these random fields are infinitely divisible.Comment: 5 ...
Karcher, Wolfgang   +2 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Excursion sets of stable random fields [PDF]

open access: yes, 2007
Studying the geometry generated by Gaussian and Gaussian- related random fields via their excursion sets is now a well developed and well understood subject. The purely non-Gaussian scenario has, however, not been studied at all. In this paper we look at
Adler, Robert J.   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Inference Tools for Markov Random Fields on Lattices: The R Package mrf2d

open access: yesJournal of Statistical Software, 2022
Markov random fields on two-dimensional lattices are behind many image analysis methodologies. mrf2d provides tools for statistical inference on a class of discrete stationary Markov random field models with pairwise interaction, which includes many of ...
Victor Freguglia, Nancy Lopes Garcia
doaj   +1 more source

Metamagnets in uniform and random fields

open access: yes, 1998
We study a two-sublattice Ising metamagnet with nearest and next-nearest-neighbor interactions, in both uniform and random fields. Using a mean-field approximation, we show that the qualitative features of the phase diagrams are significantly dependent ...
Galam, Serge   +2 more
core   +1 more source

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