Results 51 to 60 of about 338,729 (282)

Analysis of purely random forests bias [PDF]

open access: yes, 2014
Random forests are a very effective and commonly used statistical method, but their full theoretical analysis is still an open problem. As a first step, simplified models such as purely random forests have been introduced, in order to shed light on the ...
Arlot, Sylvain, Genuer, Robin
core   +2 more sources

On PAC-Bayesian Bounds for Random Forests

open access: yes, 2019
Existing guarantees in terms of rigorous upper bounds on the generalization error for the original random forest algorithm, one of the most frequently used machine learning methods, are unsatisfying.
Igel, Christian   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A comparison among interpretative proposals for Random Forests

open access: yesMachine Learning with Applications, 2021
The growing success of Machine Learning (ML) is making significant improvements to predictive models, facilitating their integration in various application fields.
Massimo Aria   +2 more
doaj   +1 more source

Training Big Random Forests with Little Resources

open access: yes, 2018
Without access to large compute clusters, building random forests on large datasets is still a challenging problem. This is, in particular, the case if fully-grown trees are desired.
Beazley David M.   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Assessing Predictability of Marine Heatwaves With Random Forests

open access: yesGeophysical Research Letters, 2022
Marine heatwaves (MHWs) have increased in frequency and duration over the last century and are expected to intensify in the future. Such events have become an increasing threat for marine ecosystems and subsequently the economies and populations that ...
K. Giamalaki   +2 more
doaj   +1 more source

Reliable ABC model choice via random forests

open access: yes, 2015
Approximate Bayesian computation (ABC) methods provide an elaborate approach to Bayesian inference on complex models, including model choice. Both theoretical arguments and simulation experiments indicate, however, that model posterior probabilities may ...
Cornuet, Jean-Marie   +5 more
core   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Determining vertical structure of forests in Poland using a semi-automated approach based on ALS data

open access: yesEcological Indicators
The vertical structure of the forest is one of the key characteristics of forest management, influencing biodiversity, resource competition, and various ecological processes. Despite its importance, determining the vertical structure of stands over large
Piotr Janiec   +4 more
doaj   +1 more source

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