Results 61 to 70 of about 2,068,010 (305)

Two Applications of Random Spanning Forests [PDF]

open access: yes, 2017
International audienceWe use random spanning forests to find, for any Markov process on a finite set of size n and any positive integer m
Gaudillière, Alexandre   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Design of Probabilistic Random Forests with Applications to Anticancer Drug Sensitivity Prediction [PDF]

open access: yes, 2015
Random forests consisting of an ensemble of regression trees with equal weights are frequently used for design of predictive models. In this article, we consider an extension of the methodology by representing the regression trees in the form of ...
Ranadip Pal   +8 more
core   +1 more source

Block Forests: random forests for blocks of clinical and omics covariate data

open access: yesBMC Bioinformatics, 2019
Background In the last years more and more multi-omics data are becoming available, that is, data featuring measurements of several types of omics data for each patient. Using multi-omics data as covariate data in outcome prediction is both promising and
Roman Hornung, Marvin N. Wright
doaj   +1 more source

Prediction of unconventional protein secretion by exosomes

open access: yesBMC Bioinformatics, 2021
Motivation In eukaryotes, proteins targeted for secretion contain a signal peptide, which allows them to proceed through the conventional ER/Golgi-dependent pathway.
Alvaro Ras-Carmona   +2 more
doaj   +1 more source

Estimation of Vegetation Indices With Random Kernel Forests

open access: yesIEEE Access, 2023
Vegetation indexes help perform precision farming because they provide useful information regarding moisture, nutrient content, and crop health. Primary sources of those indexes are satellites and unmanned aerial vehicles equipped with expensive ...
Dmitry A. Devyatkin
doaj   +1 more source

Banzhaf Random Forests

open access: yesCoRR, 2015
Random forests are a type of ensemble method which makes predictions by combining the results of several independent trees. However, the theory of random forests has long been outpaced by their application. In this paper, we propose a novel random forests algorithm based on cooperative game theory.
Jianyuan Sun   +3 more
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

A comparison among interpretative proposals for Random Forests

open access: yesMachine Learning with Applications, 2021
The growing success of Machine Learning (ML) is making significant improvements to predictive models, facilitating their integration in various application fields.
Massimo Aria   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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