Results 81 to 90 of about 1,191,216 (267)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Law of addition in random matrix theory
, 1996 We discuss the problem of adding random matrices, which enable us to study Hamiltonians consisting of a deterministic term plus a random term. Using a diagrammatic approach and introducing the concept of ``gluon connectedness," we calculate the density ...
't Hooft +22 more
core +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Ensemble averaging in JT gravity from entanglement in Matrix Quantum Mechanics
Journal of High Energy Physics, 2023 We consider the generalization of a matrix integral with arbitrary spectral curve ρ 0(E) to a 0+1D theory of matrix quantum mechanics (MQM). Using recent techniques for 1D quantum systems at large-N, we formulate a hydrodynamical effective theory for the
Gabriele Di Ubaldo, Giuseppe Policastro
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Quantum chaos and regularity in $\Phi^4$ theory
, 2003 We check the eigenvalue spectrum of the $\Phi^{4}_{1+1}$ Hamiltonian against Poisson or Wigner behavior predicted from random matrix theory. We discuss random matrix theory as a tool to discriminate the validity of a model Hamiltonian compared to an ...
Bittner +11 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Random Triangle Theory with Geometry and Applications
, 2015 What is the probability that a random triangle is acute? We explore this old question from a modern viewpoint, taking into account linear algebra, shape theory, numerical analysis, random matrix theory, the Hopf fibration, and much much more.
Edelman, Alan, Strang, Gilbert
core +1 more source
Riemann Zeros and Random Matrix Theory [PDF]
Milan Journal of Mathematics, 2010 This is a survey article on the interaction between zeta functions and random matrix theory. Their connection originates from \textit{H. L. Montgomery}'s pair-correlation conjecture [in: Analytic Number Theory, Proc. Sympos. Pure Math. 24, 181--193 (1973; Zbl 0268.10023)], from which the story starts.
openaire +4 more sources
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source