Results 141 to 150 of about 561,925 (299)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Separated Random Number Generators for Virtual Machines

, 2017
High quality random numbers are essential for secure servers, alas virtual machines suffer from low entropy. The generation of hard to predict random numbers is a crucial problem. Moreover, existing solutions can pose severe security risks, e.g.
Hoffmann, Jörn, Fritzsch, Clemens, Bogdan, Martin   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Permutation and sampling with maximum length CA for pseudorandom number generation

, 2007
In this paper, we study the effect of dynamic permutation and sampling on the randomness quality of sequences generated by cellular automata (CA). Dynamic permutation and sampling have not been explored in previous CA work and a suitable implementation ...
Wijaya, S, Guan, SU, Tan, SK
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Quantum LFSR Structure for Random Number Generation Using QCA Multilayered Shift Register for Cryptographic Purposes. [PDF]

Sensors (Basel), 2022
Kim HI, Jeon JC.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

RandseqR: An R Package for Describing Performance on the Random Number Generation Task. [PDF]

Front Psychol, 2021
Oomens W, Maes JHR, Hasselman F, Egger JIM.   +3 more
europepmc   +1 more source

Uniform Random Number Generators [PDF]

1998 Winter Simulation Conference. Proceedings (Cat. No.98CH36274), 2002
openaire   +1 more source

Parallel Random Number Generation on KSR1

, 1993
In this note, parallel random number generation on the KSR1 parallel computer is discussed. The random number generators available for the KSR1 are sketched, and performance measurements done at the KSR1-32 system in Mannheim are presented, focusing on ...
Michael Hennecke
core