Results 111 to 120 of about 884,278 (306)

Moment conditions in strong laws of large numbers for multiple sums and random measures

open access: yes, 2017
The validity of the strong law of large numbers for multiple sums Sn of independent identically distributed random variables Zk , k ≤ n, with r-dimensional indices is equivalent to the integrability of |Z|(log+|Z|)r⁻¹, where Z is the generic summand. We
Klesov, Oleg   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

If Not Only Numbers Count: Allocation of Equal Chances [PDF]

open access: yes
It is assumed that medical guidelines specify the appropriate amount of a divisible good which each individual should receive. Individual requirements and probabilities that the treatment is successful if an appropriate amount is received differ.
Marlies Ahlert
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Binarizations in random number generation

open access: yes2016 IEEE International Symposium on Information Theory (ISIT), 2016
Extracting procedures produce unbiased random bits from biased coin flips. Binarizations take inputs from an m-faced dice and produce bit sequences to be fed into a (binary) extracting procedure to obtain random bits, and this can be done in an entropy-preserving manner, without loss of information. Such a procedure has been proposed by Zhou and Bruck [
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Asymptotic Equivalence of Probabilistic Serial and Random Priority Mechanisms [PDF]

open access: yes
The random priority (random serial dictatorship) mechanism is a common method for assigning objects to individuals. The mechanism is easy to implement and strategy-proof.
Yeon-Koo Che, Fuhito Kojima
core  

pratheekbalaji/randomNumberGenerator: Generating Random Numbers

open access: yes, 2020
Scripts that generate random numbers and visualize ...
pratheekbalaji
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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